Localized Resectable Adult Primary Liver Cancer
Localized and Locally Advanced Unresectable Adult Primary Liver Cancer
Advanced Adult Primary Liver Cancer
Recurrent Adult Primary Liver Cancer

A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

Treatment of localized resectable adult primary liver cancer may include the following:

• Surgery (partial hepatectomy).
• Surgery (total hepatectomy) and liver transplant.
• A clinical trial of regional or systemic chemotherapy or biologic therapy following surgery.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with localized resectable adult primary liver cancer.

Treatment of localized and locally advanced unresectable adult primary liver cancer may include the following:

• Surgery (cryosurgery or radiofrequency ablation).
• Chemotherapy (chemoembolization, regional chemotherapy, or systemic chemotherapy).
• Percutaneous ethanol injection.
• Surgery (total hepatectomy) and liver transplant.
• Radiation therapy with radiosensitizers.
• A clinical trial of a combination of surgery, chemotherapy, and radiation therapy. Hyperthermia therapy may also be used. Chemotherapy and radiation therapy may be used to shrink the tumor before surgery.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with localized unresectable adult primary liver cancer.

There is no standard treatment for advanced adult primary liver cancer. Patients may consider taking part in a clinical trial. Treatment may be a clinical trial of biologic therapy, chemotherapy, and/or radiation therapy with or without radiosensitizers. These treatments may be given as palliative therapy to help relieve symptoms and improve the quality of life.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with advanced adult primary liver cancer.

Treatment of recurrent adult primary liver cancer may include the following:

• Surgery (partial hepatectomy).
• Surgery (total hepatectomy) and liver transplant.
• Chemotherapy (chemoembolization or systemic chemotherapy).
• Percutaneous ethanol injection.
• A clinical trial of a new therapy.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with recurrent adult primary liver cancer.

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