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Neuroprotectants as Medical Countermeasures against Chemical Threat Agents: Request for Information (RFI)
Release Date: March 5, 2007
Announcement Number: NOT-NS-07-007
Funding Contact: David Jett, Ph.D.
Program Area: Office of Translational Research
Brief Description:
The National Institute of Neurological Disorders and Stroke (NINDS) is seeking information on the development of therapeutics
with indications for protecting the nervous system from cellular and tissue damage caused by acute exposure to chemical threat
agents. Chemical threat agents are toxic chemicals that could be used in a terrorist attack against civilians, or chemicals
that could be released at toxic levels by accident or natural disaster. Since chemically-induced neurological damage may
share common mechanisms with damage caused by trauma and/or disease, the NINDS also requests information on general molecular
and cellular processes of neurodegeneration, and how an understanding of these processes may be used to develop safe and effective
medical countermeasures against chemical threats.
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