Testing Status of Agents at NTP
HC red 3
CASRN: 2871-01-4
Formula: C8-H11-N3-O3
Synonyms/Common Names:
- 2-((4-AMINO-2-NITROPHENYL)AMINO)ETHANOL (9CI)
- RED 3, HC
Known Uses:
DYE IN SEMI-PERMANENT HAIR DYES. (TDB)
Short-Term Toxicity
- 14-Day (Gavage)
(C54922) Completed
- NTIS No. PB86-188075
(Peer Review 03/29/1985)
Citation: Toxicology and Carcinogenesis Studies of HC Red No. 3 [2,((Amino-2-nitrophenyl)amino)ethanol] (CAS No. 2871-01-4) In F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB86-188075
(Peer Review 03/29/1985)
- 13-Week (Gavage)
(C54922) Completed
- NTIS No. PB86-188075
(Peer Review 03/29/1985)
Citation: Toxicology and Carcinogenesis Studies of HC Red No. 3 [2,((Amino-2-nitrophenyl)amino)ethanol] (CAS No. 2871-01-4) In F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,62,1000, M: 0,15,250 MG/KG/10 PER GROUP
- NTIS No. PB86-188075
(Peer Review 03/29/1985)
Long-Term Carcinogenicity
- 2-YEAR (Gavage)
(C54922) Report Complete
- TR-281 (NTIS No. PB86-188075)
(Peer Review 03/29/1985)
Toxicology and Carcinogenesis Studies of HC Red No. 3 [2,((Amino-2-nitrophenyl)amino)ethanol] (CAS No. 2871-01-4) In F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats No Evidence
- Female Rats No Evidence
- Male Mice Equivocal Evidence
- Female Mice Inadequate Study
- Dose: R: 0,250,500, M: 0,125,250 MG/KG/50 PER GROUP
- TR-281 (NTIS No. PB86-188075)
(Peer Review 03/29/1985)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(828169) Completed
- Chromosome Aberation Positive
- Sister Chromatid Exchange Positive
- Mouse Lymphoma
(063330) Completed
- Positive
- Salmonella
(890915) Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
- Positive
Web page last updated on January 22, 2009