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Noteworthy Clinical Trials

Treatment Trials
The ALTTO Breast Cancer Trial 1
(Posted: 03/14/2008) - A collection of material about the Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation, or ALTTO, study that will compare the targeted agents lapatinib and trastuzumab alone, in sequence, or in combination as adjuvant therapy for HER2-positive breast cancer.

The TAILORx Breast Cancer Trial 2
(Posted: 05/23/2006) - A collection of material about the Trial Assigning IndividuaLized Options for Treatment (Rx), or TAILORx, which will examine whether a molecular test can assign women with early-stage breast cancer to the most appropriate and effective treatment.

Clinical Trials Covered Under the Medicare Anti-Cancer Drugs National Coverage Decision 3
(Posted: 01/09/2006, Reviewed: 11/12/2008) - Information for patients and doctors about expanded coverage for the experimental and routine services provided to Medicare beneficiaries enrolled in certain cancer trials sponsored by the National Cancer Institute.
Prevention Trials
The Breast Cancer Prevention Trial 4
(Posted: 11/09/2001, Updated: 12/11/2008) - A collection of material about the Breast Cancer Prevention Trial (BCPT).

The SELECT Prostate Cancer Prevention Trial 5
(Posted: 07/24/2001, Updated: 12/02/2008) - A collection of material about SELECT (Selenium and Vitamin E Cancer Prevention Trial), which sought to determine whether these two dietary supplements could protect against prostate cancer.

The Prostate Cancer Prevention Trial 6
(Posted: 05/22/2003, Updated: 12/12/2007) - A collection of material about a study designed to see whether the drug finasteride (trade name Proscar) can prevent prostate cancer in men ages 55 and older.

Study of Tamoxifen and Raloxifene (STAR) Trial 7
(Posted: 07/27/2000, Updated: 09/12/2007) - A collection of material about the Study of Tamoxifen and Raloxifene, or STAR trial, one of the largest-ever breast cancer prevention studies.
Testing and Screening
National Lung Screening Trial (NLST) 8
NLST, the National Lung Screening Trial, is a research study sponsored by the National Cancer Institute for men and women at risk for lung cancer.

Digital Mammographic Imaging Screening Trial 9
DMIST, the Digital Mammographic Imaging Screening Trial, is a research study sponsored by the U.S. National Cancer Institute to compare digital mammography to conventional screen-film mammography.

Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial 10
A large-scale clinical trial to determine whether certain cancer screening tests reduce deaths from prostate, lung, colorectal, and ovarian cancer. In addition, there are numerous epidemiologic and ancillary studies going on that will answer other crucial questions about these cancers and these screening tests.



Table of Links

1http://www.cancer.gov/clinicaltrials/digestpage/ALTTO
2http://www.cancer.gov/clinicaltrials/digestpage/TAILORx
3http://www.cancer.gov/clinicaltrials/developments/NCD179N
4http://www.cancer.gov/clinicaltrials/digestpage/BCPT
5http://www.cancer.gov/clinicaltrials/digestpage/SELECT
6http://www.cancer.gov/pcpt
7http://www.cancer.gov/clinicaltrials/digestpage/STAR
8http://www.cancer.gov/nlst
9http://www.cancer.gov/dmist
10http://dcp.cancer.gov/programs-resources/groups/ed/programs/plco