Testing Status of Agents at NTP
C.I. Direct brown 95
CASRN: 16071-86-6
Formula: C31-H18-CU-N6-O9-S.2NA
Synonyms/Common Names:
- BROWN 95, C.I. DIRECT
- (5-((4'-((2,6-DIHYDROXY-3-((2-HYDROXY-5-SULFOPHENYL)-AZO)(1,1'-BIPHENYL)-4-YL)AZO)-2-HYDROXYBENZOATO(4-))-CUPRATE(2-)DIS0DIUM SALT (9CI)
Known Uses:
DYE FOR TEXTILES, LEATHER, PLASTICS, PAPER
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C54568) Completed
- NTIS No. PB280204
(Peer Review 03/06/1978)
Citation: 13-Week Subchronic Toxicity Studies of Direct Blue 6, Direct Black 38, and Direct Brown 95 Dyes - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,190,375,750,1500,3000, MM: 0,750,1500,3000,6000,12500, FM: 0,375,750,1500,3000,6000 PPM/10 PER GROUP
- NTIS No. PB280204
(Peer Review 03/06/1978)
- 13-Week (Dosed-Feed)
(C54568) Report Complete
- NTIS No. PB280204
(Peer Review 03/06/1978)
Citation: 13-Week Subchronic Toxicity Studies of Direct Blue 6, Direct Black 38, and Direct Brown 95 Dyes - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,190,375,750,1500,3000, MM: 0,750,1500,3000,6000,12500, FM: 0,375,750,1500,3000,6000 PPM/10 PER GROUP
- NTIS No. PB280204
(Peer Review 03/06/1978)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(754489) Completed
- Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
- Chromosome Aberation Negative
- Sister Chromatid Exchange Inconclusive
- Drosophila
(205697) Completed
- Citation: Yoon, J.S., Mason, J.M., Valencia, R., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 349-367
- Reciprocal Translocation/Sex-Linked Recessive Lethal Negative
- Mouse Lymphoma
(162126) Completed
- Positive
- Salmonella
(306945) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Weakly Positive
- Salmonella
(870768) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Negative
- Salmonella Reduction
(599630) Completed
- Citation: Reid, T., Morton K., and King, C. Mutagenicity of azo dyes following metabolism by different reductive/oxidative systems. Environ. Mutagen. Vol. 6 (1984) 705-717
- Positive
Organ Systems Toxicity
- GD 6-15 Conventional Teratology (Subcutaneous Injection)
(T0139) Completed
- F Mice: Swiss
- Dose: 0, 20, 40, 60, 80, 100 MG/KG/DAY
Web page last updated on January 22, 2009