National Institute of Allergy and Infectious Diseases
Link to NIAID Home Page Link to NIAID Home Page Link to NIH Home Page
NIAID Home Health & Science Research Funding Research News & Events Labs at NIAID About NIAID

Syphilis
 Cause
 Transmission
 Symptoms
 Diagnosis
 Treatment
 Prevention
 Complications
 Research


Syphilis

Syphilis is a sexually transmitted, bacterial infection that initially causes genital ulcers (sores). If untreated, the disease will progress to more serious stages of infection, including blindness and nerve damage.

An ancient disease, syphilis is still of major importance today. Although syphilis rates in the United States declined by almost 90 percent from 1990 to 2000, the number of cases rose from 5,979 in 2000 to 9,756 in 2006. In a single year, from 2005 to 2006, the rate of syphilis jumped 12 percent.

There also was a dramatic change in which groups the disease affects the most. An increase of primary and secondary syphilis in males has driven the overall rate increase for the U.S. to 54 percent from 2002 to 2006. Between 2005 and 2006, the number of cases in men increased 11.8 percent, reflecting an increase in syphilis in men who have sex with men. Additionally, an increase of 11.4 percent was observed in African-American women from 2005 to 2006.

HIV infection and syphilis are linked. Syphilis increases the risk of transmitting as well as getting infected with HIV.

Understanding Syphilis


Volunteer for Clinical Studies
Volunteer for NIAID-funded clinical studies related to syphilis on ClinicalTrials.gov.

See Also

  • Sexually Transmitted Infections
  • Sexually Transmitted Infections News Releases
  • Related Links

    View a list of links for more information about the syphilis.

    E-mail Icon E-mail this page
    Print Icon Print this page

    Volunteer for Clinical Studies
    Volunteer for NIAID-funded clinical studies related to syphilis on ClinicalTrials.gov.

    See Also

  • Sexually Transmitted Infections
  • Sexually Transmitted Infections News Releases
  • Related Links

    View a list of links for more information about the syphilis.