Summaries & Associations of Study Results
TR-326 Ethylene Oxide
Target Organs and Levels of Evidence
NTP Technical Report Number 326
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| ETHYLENE OXIDE 75-21-8 |
08/19/86 | ACCELERATES RIPENING IN FRUIT AND MATURING OF TOBACCO LEAVES. FUNGISTAT. ROCKET PROPELLANT. FUMIGANT FOR FOODSTUFFS AND TEXTILES. ORGANIC SYNTHESIS. STERILIZE SURGICAL INSTRUMENTS. CHEMICAL INTERMEDIATE. (TDB) | Inhalation 0,50,100 PPM/50 PER GROUP | Battelle Northwest Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MM: CLEAR EVIDENCE | LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 5/50 11/50 11/50; ALVEOLAR/BRONCHIOLAR CARCINOMA 6/50 10/50 16/50 | |||
| HARDERIAN GLAND: CYSTADENOMA 1/43 9/44 8/42 | ||||
| FM: CLEAR EVIDENCE | LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 2/49 4/48 17/49; ALVEOLAR/BRONCHIOLAR CARCINOMA 0/49 1/48 7/49 | |||
| HARDERIAN GLAND: CYSTADENOMA 1/46 6/46 8/47 | ||||
| UTERUS/CERVIX: ADENOCARCINOMA 0/49 1/47 5/49 | ||||
| MAMMARY GLAND: ADENOCARCINOMA 1/49 6/48 4/49; ADENOSQUAMOUS CARCINOMA 0/49 2/48 2/49 | ||||
| HEMATOPOIETIC SYSTEM: LYMPHOMA 9/49 6/48 22/49 | ||||
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