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Infectious cDNA Clone of GB Virus B and Uses Thereof

Description of Invention:
The current invention provides nucleic acid sequences comprising the genomes of infectious GB virus B, the most closely related member of the Flaviviridae to hepatitis C virus (HCV). It also covers chimeric GBVB-HCV sequences and polypeptides for use in the development of vaccines and diagnostic assays for HCV and the development of screening assays for the identification of antiviral agents for HCV. Additional information can be found in Bukh et al. (1999), Virology 262, 470-478.

Inventors:
Jens Bukh (NIAID)
Masayuki Yanagi (NIAID)
Robert H. Purcell (NIAID)
Suzanne U. Emerson (NIAID)

Patent Status:
DHHS Reference No. E-173-1999/0 --
U.S. Patent No. 7,129,342 issued 31 Oct 2006

Related Technologies:

DHHS Reference No. E-050-1998/0 -- "Cloned Genomes Of Infectious Hepatitis C Virus And Uses Thereof"

DHHS Reference No. E-100-1999/0 -- "Cloned Genome of Infectious Hepatitis C Virus of Genotype 2a and Uses Thereof"

DHHS Reference No. E-102-1999/0 -- "HCV/BVDV Chimeric Genomes and Uses Thereof"

Portfolios:
Infectious Diseases

Infectious Diseases -Vaccines-Viral
Infectious Diseases -Research Materials
Infectious Diseases -Vaccines


For Additional Information Please Contact:
RC Tang JD, LLM
NIH Office of Technology Transfer
6011 Executive Blvd, Suite 325
Rockville, MD 20852-3804
Phone: 301/435-5031
Email: tangrc@mail.nih.gov
Fax: 301/402-0220

Web Ref: 490

Last Updated On: 10/02


 
 
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