National Toxicology Program

CASRN: 156-62-7

Formula: C-H2-N2.CA

Synonyms/Common Names:

• CYANAMIDE, CALCIUM SALT (1:1) (9CI)

Known Uses:

FERTILIZER, DEFOLIANT, HERBICIDE, PESTICIDE; HARDENING IRON AND STEEL

Short-Term Toxicity

• 13-WEEK (Dosed-Feed)  (C02937) Completed 
  • NTIS No. PB293625  (Peer Review 12/13/1978)
    Citation: Bioassay of Calcium Cyanamide for Possible Carcinogenicity (CAS No. 156-62-7)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R: 0,400,1500, M: 0,1500,30000 PPM/5 PER GROUP

Long-Term Carcinogenicity

• 2-YEAR (Dosed-Feed)  (C02937) Report Complete 
  • TR-163 (NTIS No. PB293625)  (Peer Review 12/13/1978)
    Bioassay of Calcium Cyanamide for Possible Carcinogenicity (CAS No. 156-62-7)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Negative 
  • Female Rats Negative 
  • Male Mice Negative 
  • Female Mice Negative 
  • Dose: R: 0,100,200, M: 0,100,400 PPM/50 PER GROUP

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (893256) Completed 
  • Chromosome Aberation Negative 
  • Sister Chromatid Exchange Negative 
• Drosophila  (522663) Completed 
  • Citation: Yoon, J.S., Mason, J.M., Valencia, R., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 349-367
  • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
• Mouse Lymphoma  (430294) Completed 
  •  Negative 
• Salmonella  (035712) Completed 
  • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
  •  Inconclusive 
• Salmonella  (232717) Completed 
  • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
  •  Weakly Positive