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Disease Damage Core Set Measures

Myositis Disease Damage Index (MDI)

• Description:

  This partially validated tool measures the degree of disease damage of all organ systems. It is composed of a series of organ-specific questions relating to the presence or absence of a given sign or symptom or problem to measure the extent of damage, and an overall rating of the disease damage of each system using a 10 cm. visual analogue scale to measure the severity of damage.

• Download

  • Myositis Damage Index -- Word Format (http://www.niehs.nih.gov/research/resources/collab/imacs/http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/mdi.doc)   (93.0 KB) Myositis Damage Index -- PDF Format (http://www.niehs.nih.gov/research/resources/collab/imacs/http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/mdi.pdf)   (160 KB)

• Related educational material:

  • MDI Cutaneous Teaching Slide Set (http://www.niehs.nih.gov/research/resources/collab/imacs/http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/mdi/09_mdi_cutaneous_teaching_slide_set.swf)   (44.7 KB )
  • MDI case examples -- Word Format (http://www.niehs.nih.gov/research/resources/collab/imacs/http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/mdi-global_damage_examples.doc)   (93.0 KB ) MDI Case examples -- PDF Format (http://www.niehs.nih.gov/research/resources/collab/imacs/http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/mdi-global_damage_examples.pdf)   (106 KB )

• Reference:

  1. Isenberg DA, Allen E, Farewell V, Ehrenstein MR, Hanna MG, Lundberg IE, Oddis C, Pilkington C, Plotz P, Scott D, Vencovsky J, Cooper R, Rider L, Miller F; International Myositis and Clinical Studies Group (IMACS). International consensus outcome measures for patients with idiopathic inflammatory myopathies. Development and initial validation of myositis activity and damage indices in patients with adult onset disease. Rheumatology (Oxford). 2004 Jan;43(1):49-54. Epub 2003 Jul 16. Pub Med (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12867580)

Physician Global Assessment of Disease Damage

• Description:

  This partially validated tool measures the global evaluation by the treating physician of the overall disease damage of the patient at the time of assessment using a 10 cm. visual analogue scale and a 5 point Likert scale.

• Download:

  • Physician Global Damage -- Word Format (http://www.niehs.nih.gov/research/resources/collab/imacs/http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/phys_glob_damage.doc)   (28.0 KB) Physician Global Damage -- PDF Format (http://www.niehs.nih.gov/research/resources/collab/imacs/http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/phys_glob_damage.pdf)   (69.0 KB)

• Related educational material:

  • Example Cases for Disease Damage Assessment -- Word Format (http://www.niehs.nih.gov/research/resources/collab/imacs/http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/dis_dam_assess.doc)   (78.5 KB) Example Cases for Disease Damage Assessment -- PDF Format (http://www.niehs.nih.gov/research/resources/collab/imacs/http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/dis_dam_assess.pdf)   (154 KB)

• Reference:

  1. Rider LG, Feldman BM, Perez MD, Rennebohm RM, Lindsley CB, Zemel LS, Wallace CA, Ballinger SH, Bowyer SL, Reed AM, Passo MH, Katona IM, Miller FW, Lachenbruch PA. Development of validated disease activity and damage indices for the juvenile idiopathic inflammatory myopathies: I. Physician, parent, and patient global assessments. Juvenile Dermatomyositis Disease Activity Collaborative Study Group. Arthritis Rheum. 1997 Nov;40(11):1976-83. Pub Med (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9365086)

Patient/Parent Global Assessment of Disease Damage

• Description:

  This partially validated tool measures the global evaluation by the patient, or by the parent if the patient is a minor, of the patient's overall disease damage at the time of assessment using a 10 cm. visual analogue scale.

• Download

  • Patient/Parent Global Assessment of Disease Damage -- Word Format (http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/pt_parent_glob_damage.doc)   (30.5 KB) Patient/Parent Global Assessment of Disease Damage -- PDF Format (http://www.niehs.nih.gov/research/resources/collab/imacs/docs/damage/pt_parent_glob_damage.pdf)   (104 KB)

• Reference:

  1. Rider LG, Feldman BM, Perez MD, Rennebohm RM, Lindsley CB, Zemel LS, Wallace CA, Ballinger SH, Bowyer SL, Reed AM, Passo MH, Katona IM, Miller FW, Lachenbruch PA. Development of validated disease activity and damage indices for the juvenile idiopathic inflammatory myopathies: I. Physician, parent, and patient global assessments. Juvenile Dermatomyositis Disease Activity Collaborative Study Group. Arthritis Rheum. 1997 Nov;40(11):1976-83. Pub Med (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9365086)

Muscle Strength Testing - Manual Muscle Testing (MMT)

• This tool is available under the toolset Disease Activity - Core Set

Functional Assessment Tools - HAQ, CHAQ

• This tool is available under the toolset Disease Activity - Core Set

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Last Reviewed: October 30, 2007