Trans-NIH Mouse Initiative
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Mice

RFA on Development of Behavioral Methods for Drug Abuse Studies in the Mouse

The National Institute on Drug Abuse (NIDA) is soliciting applications to develop or adapt behavioral models and methods for the mouse in order to advance the understanding of drug abuse and addiction. NIDA has initiated this Request for Applications to increase the number of laboratories capable of using behavioral approaches to study and develop models of drug abuse and addiction in the mouse. Appropriate studies for this RFA might include, but are not limited to, the following areas: (1)The development of methods for studying, in the mouse, a variety of behaviors involved in or related to drug taking, drug seeking, or motivational processes. (2) Phenotypic characterization of behaviors that are related to drug taking and drug seeking, or indicative of related central motivational states in different laboratory mouse strains or genetically altered mice. (3)The development of methods for rapid and/or automated phenotypic screening, such as automated methods for measuring drug directed or related behaviors, or for measuring behavioral responsivity to drugs of abuse or potential therapeutic agents. (4)The development of novel methods of drug self administration, which are less technically difficult and more easily implemented than traditional methods, for rapid screening of behavioral phenotype.

This RFA will use the R21 grant mechanism. The NIDA intends to commit approximately $1,000,000 in FY 2001 to fund 10-15 new grants in response to this RFA.

Letters of Intent are due July 21, 2000. The application receipt date is August 22, 2000.

The full text of this RFA can be found at:
http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-01-002.html

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