Summaries & Associations of Study Results
TR-501 p,p'-Dichlorodiphenyl Sulfone
Target Organs and Levels of Evidence
NTP Technical Report Number 501
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| P,P'-DICHLORODIPHENYL SULFONE 80-07-9 |
05/18/00 | STARTING MATERIAL IN PROD'N OF PLASTICS | Dosed-Feed MR: 0, 10, 30, OR 100 PPM; FR & MICE: 0, 30, 100, OR 300 PPM; 50/SEX/DOSE | Battelle Columbus Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LIVER: CENTRILOBULAR HYPERTROPHY | |||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LIVER: CENTRILOBULAR HYPERTROPHY; BILE DUCT HYPERPLASIA; CENTRILOBULAR DEGENERATION | |||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LIVER: CENTRILOBULAR HYPERTROPHY | |||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LIVER: CENTRILOBULAR HYPERTROPHY; EOSINOPHILIC FOCUS | |||
Web page last updated on February 10, 2006
