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Skin Cancer Prevention (PDQ®)
Patient Version   Health Professional Version   Last Modified: 12/19/2008



What is prevention?






General Information About Skin Cancer






Skin Cancer Prevention






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Changes to This Summary (12/19/2008)






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Skin Cancer Prevention

Key Points for This Section


Avoiding risk factors and increasing protective factors may help prevent cancer.

Avoiding cancer risk factors such as smoking, being overweight, and lack of exercise may help prevent certain cancers. Increasing protective factors such as quitting smoking, eating a healthy diet, and exercising may also help prevent some cancers. Talk to your doctor or other health care professional about how you might lower your risk of cancer.

Being exposed to ultraviolet radiation is a risk factor that may increase the risk of skin cancer.

Studies suggest that being exposed to ultraviolet (UV) radiation and the sensitivity of a person’s skin to UV radiation are risk factors for skin cancer. UV radiation is the name for the invisible rays that are part of the energy that comes from the sun. Sunlamps and tanning booths also give off UV radiation.

Risk factors for nonmelanoma and melanoma cancers are not the same:

  • Nonmelanoma skin cancer: The total amount of time the skin is exposed to UV radiation may affect the risk of nonmelanoma skin cancer. Spending more time in the sun may increase the risk. People may have an increased risk of nonmelanoma skin cancer if their skin burns easily in the sun.


  • Melanoma skin cancer: Being exposed to strong UV radiation for short periods (as with sunburns), especially in childhood and teen years, may increase the risk of melanoma. People may have an increased risk of melanoma from UV radiation if they burn easily in the sun or have freckles or a lot of moles.


It is not known if protecting skin from sunlight and other UV radiation decreases the risk of skin cancer.

It is not known if nonmelanoma skin cancer risk is decreased by staying out of the sun, using sunscreens, or wearing long sleeve shirts, long pants, sun hats, and sunglasses when outdoors.

Sunscreen may help decrease the amount of UV radiation to the skin. One study found that wearing sunscreen can help prevent actinic keratoses, scaly patches of skin that may become squamous cell carcinoma. However, the use of sunscreen has not been proven to lower the risk of melanoma skin cancer.

Although protecting the skin and eyes from the sun has not been proven to lower the chance of getting skin cancer, skin experts suggest the following:

  • Use sunscreen that protects against UV radiation.
  • Do not stay out in the sun for long periods of time, especially when the sun is at its strongest.
  • Wear long sleeve shirts, long pants, sun hats, and sunglasses, when outdoors.

Cancer prevention clinical trials are used to study ways to prevent cancer.

Cancer prevention clinical trials are used to study ways to lower the risk of developing certain types of cancer. Some cancer prevention trials are conducted with healthy people who have not had cancer but who have an increased risk for cancer. Other prevention trials are conducted with people who have had cancer and are trying to prevent another cancer of the same type or to lower their chance of developing a new type of cancer. Other trials are done with healthy volunteers who are not known to have any risk factors for cancer.

The purpose of some cancer prevention clinical trials is to find out whether actions people take can prevent cancer. These may include eating fruits and vegetables, exercising, quitting smoking, or taking certain medicines, vitamins, minerals, or food supplements.

New ways to prevent skin cancer are being studied in clinical trials.

Clinical trials are taking place in many parts of the country. Information about clinical trials can be found in the Clinical Trials section of the NCI Web site. Check for clinical trials in NCI's PDQ Cancer Clinical Trials Registry for skin cancer prevention trials that are now accepting patients.

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