Testing Status of Agents at NTP
Sodium diethyldithiocarbamate
CASRN: 148-18-5
Formula: C5-H11-N-S2.NA (TSCAIN) - C5-H10-N-NA-S2
Synonyms/Common Names:
- DIETHYLCARBAMODITHIOIC ACID SODIUM SALT (9CI)
Known Uses:
ANALYSIS OF METALS, TREATMENT FOR METAL POISONING & WILSON'S DISEASE, INTERMED. IN FUNGICIDE & RUBBER PRODUCTION (HSDB 1990)
Short-Term Toxicity
- 13-WEEK (Dosed-Feed)
(C02835) Completed
- NTIS No. PB293833
(Peer Review 12/13/1978)
Citation: Bioassay of Sodium Diethyldithiocarbamate for Possible Carcinogenicity (CAS No. 148-18-5) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,1250,40000, M: 0,2500,10000 PPM/5 PER GROUP
- NTIS No. PB293833
(Peer Review 12/13/1978)
Long-Term Carcinogenicity
- 2-YEAR (Dosed-Feed)
(C02835) Report Complete
- TR-172 (NTIS No. PB293833)
(Peer Review 12/13/1978)
Bioassay of Sodium Diethyldithiocarbamate for Possible Carcinogenicity (CAS No. 148-18-5) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- Dose: R: 0,1250,2500, M: 0,500,4000 PPM/50 PER GROUP
- TR-172 (NTIS No. PB293833)
(Peer Review 12/13/1978)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(552900) Completed
- Citation: Loveday, K.S., Lugo, M.H., Resnick, M.A., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro II: Results with 20 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 60-94
- Chromosome Aberation Negative
- Sister Chromatid Exchange Negative
- Mouse Lymphoma
(456551) Completed
- Citation: McGregor, D., Brown, A., Howgate, S., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. IV: 27 coded chemicals. Environ. Molec. Mutagen. Vol. 17 (1991) 196-219
- Positive
- Salmonella
(965008) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Negative
Web page last updated on January 22, 2009