The Rapid Access to Intervention Development (RAID) program is designed to assist translation to the clinic of novel anticancer therapeutic interventions, either synthetic, natural product, or biologic, arising in the academic community.

RAID PROPOSALS MUST BE SUBMITTED ELECTRONICALLY AND ARE ACCEPTED TWICE YEARLY (FEBRUARY 1 AND AUGUST 1). THE APPLICATIONS ARE DUE BY 5 PM ET ON THE DEADLINE DATES USING THE ON-LINE RAID SUBMISSION FORMAT. THE RAID SUBMISSION PROCESS WILL BE AVAILABLE (30) DAYS PRIOR TO THE DEADLINE. NO APPLICATION WILL BE ACCEPTED PAST THE DEADLINE FOR ANY REASON. IT IS HIGHLY ADVISABLE THAT APPLICANTS BEGIN THE SUBMISSION PROCESS EARLY.

The applications are reviewed by a panel of experts within three months of receipt. Review criteria include strength of hypothesis, scientific novelty, and cost/benefit.

RAID is not a grant mechanism. Approved applications to RAID gain access to the drug development contract resources of the Developmental Therapeutics Program. The output of these studies is provided to the originating investigator, and may include GMP synthesized material, formulation research, pharmacological methods, or IND-directed toxicology, for support of an investigator-held IND application and clinical trials. RAID does not sponsor clinical trials.

Instructions for the Online Submission of Your RAID Application

    Submission of a RAID application requires a username and password. If you already have these items, proceed to Step 3.

  1. To register with NCI for a username and password, please proceed to http://dtp.nci.nih.gov/docs/raid/raidapp.html and click on New Registration.
  2. After obtaining your user name and password, log into the RAID Electronic Application and go to "Enter a new RAID application." Following entry of the application title, your affiliation (either academic or non-profit), and whether your product is a small molecule or biologic, you will see a listing of application elements. Each element of the application (Abstract, Background, Hypothesis, Specific Request, Justification, Uniqueness, Additional Support, Letter of Commitment, Appendix) should be created off line and saved as an Adobe PDF file. You may generate and save the application elements prior to receipt of your user certificate. The PDF file should then uploaded into the appropriate sections of the electronic form. The supplied Feasibility Questionnaire appropriate for your product should also be completed and uploaded.
  3. As each element of the application is completed and properly uploaded, that element will appear in the space marked in green on the application page. Elements yet to be completed will appear in the space marked in yellow. Application elements shown in blue are optional.

  4. Links to standard RAID forms that are required for your application appear in the explanatory text below (Biologics or Small Molecule Questionnaires).

  5. If you hit the submit key and receive an error message, either your application is not complete, or you have not used the required PDF format, or both.
  6. An investigator may submit no more than two (2) applications in a single RAID cycle.
  7. Application submissions will only be accepted beginning 30 days prior to each February 1 and August 1 deadline.
  8. Questions about the use of the electronic application format or the RAID program should be addressed to:

    RAID Coordinator
    Developmental Therapeutics Program
    6130 Executive Blvd., Room 8022
    Rockville, MD 20852
    PH: 301-496-8720
    FAX: 301-402-0831
    ncidtpraidinfo@mail.nih.gov

RAID Process and Procedures

RAID Electronic Application