Yan, Z-H., Karam, W.K., Staudinger, J.L., Medvedev, A., Ghanayem, B.I., and Jetten, A.M. Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor TAK1/TR4. J. Biol. Chem. 273:10948-10957 (1998). [Abstract]http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9556573
Adachi, H., Adams, A., Hughes, F.M., Zhang, J., Cidlowski, J.A., and Jetten, A.M. Induction of apoptosis by the novel retinoid AHPN in human T cell lymphoma cells involves caspase-dependent and independent pathways. Cell Death & Diff. 5: 973-983 (1998) [Abstract]http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9846184
Medvedev, A., Chistokhina, A., Matsuura, W., and Jetten, A.M. Regulation of the transglutaminase I gene: identification of DNA elements involved in its transcriptional control in tracheobronchial epithelial cells. J. Biol. Chem. 274: 3887-3896 (1999). [Abstract]http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9920944
Sakaue, M., Adachi, H., and Jetten, A.M. Post-transcriptional regulation of MyD118 and GADD45 in human lung carcinoma cells during 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2- naphthalene carboxylic acid-induced apoptosis. Mol. Pharmacol. 55: 668-676 (1999). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10101024]
Matsuura, H., Sakaue, M., Subbaramaiah, K., Kamitani, H., Eling, T., Dannenberg, A.J., Tanabe, T., Inoue, H., Arata, J., and Jetten, A.M. Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases. J. Biol. Chem. 274: 29138-29148 (1999). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10506169]
Jetten, A.M. and Suter U. The peripheral myelin protein 22 and epithelial membrane protein family. Structure, function, regulation and roles in disease. Progress in Nucl. Acids Res. and Mol. Biol. 64: 97-129 (2000) [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10697408]
Kurebayashi, S., Ueda, E., Sakaue, M., Patel, D., Medvedev, A., Zhang, F., and Jetten, A.M. Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis. Proc. Natl. Acad. Sci USA97: 10132- 10137 (2000) [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10963675]
Kim, S.Y., Adachi, H., Koo, J.S., and Jetten, A.M. Induction of cytochrome P450 gene CYP26 during mucous cell differentiation of normal human tracheobronchial epithelial cells. Mol. Pharm. 58: 483-490 (2000) [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10953040]
Yan, Z., and Jetten, A.M. Characterization of the repressor function of the nuclear orphan receptor retinoid receptor-related testis-associated receptor/germ cell nuclear factor. J. Biol. Chem. 275: 35077-35085 (2000) [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10940306]
Jetten, A.M., Kurebayashi, S., Ueda, E., and Sakaue, M. The ROR nuclear orphan receptor subfamily: critical regulators of multiple biological processes. Progress in Nucl. Acids Res. and Mol. Biol. 69: 205-247 (2001) [Abstract]http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11550795[]
Sakaue, M., Adachi, H., Dawson, M., and Jetten, A.M. Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK1/2. Cell Death & Diff. 8: 411-424 (2001) [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11550093]
Zhang, F., Nakanishi, G., Kurebayashi, S., Yoshino, K., Perantoni, A., Kim, Y-S., and Jetten A.M. Characterization of Glis2, a novel gene encoding a Gli-related, Kruppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis. Identification of transactivation and repressor functions. J. Biol. Chem.277: 10139-10149 (2002). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11741991]
Ueda, E., Kurebayashi, S., Sakaue, M., Backlund, M., Koller, B., and Jetten, A.M. High incidence of T cell lymphomas in mice deficient in the retinoid-related orphan receptor RORg. Cancer Res. 62: 901-909 (2002). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11830550]
Kim, Y-S., Lewandoski, M., Perantoni, A., Kurebayashi, S., and Jetten, A.M. Identification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functions. J. Biol. Chem. 277: 30901-30913 (2002). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12042312]
Yan, Z., Kim, Y-S., and Jetten, A.M. RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor. J. Biol. Chem.277: 32379-32388 (2002). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12080054]
Jetten, A. M. and Ueda, E. Retinoid-related orphan receptors (RORs): roles in cell survival, differentiation, and disease. Cell Death & Diff.9:1167-1171 (2002). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12404115]
Newman, D., Sakaue, M., Koo, J.S., Baek, S.J., Eling, T.,and Jetten, A.M. Differential regulation of nonsteroidal anti-inflammatory drug-activated gene in normal human tracheobronchial epithelial and lung carcinoma cells by retinoids. Mol. Pharm. 63:557-564 (2003). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12606762]
Yang, G., Zhang, Y-L., Buchhold, G.M., Jetten, A.M., and O’Brien, D.A. Free Full Text Analysis of germ cell nuclear factor transcripts and protein expression during spermatogenesis. Biol. Reprod. 68:1620-1630 (2003). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12606326]
Lewandoski, M., and Jetten, A.M. GLIS3, a novel member of the GLIS subfamily of Krüppel-like Zinc Finger Proteins with Repressor and Activation Functions. Nucl. Acids Res. 31: 5513-5525 (2003) [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14500813]
Daniely, Y., Liao, G., Dixon, D., Linnoila, R.I., Lori, A., Randell, S.H., Oren, M., and Jetten, A.M. Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am. J. Physiol. 287:C171-C181 (2004). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15189821]
Nakajima, T., Fujino, S., Nakanishi, G., Kim, Y-S., and Jetten, A.M.. TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4. Nucl. Acids Res. 32:4194-4204 (2004). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15302918]
Kim, Y-S., Nakanishi, G., Oudes, A.J., Kim, K.H., Wang, H., Kilpatrick, D.L., and Jetten, A.M. TSP57: a novel gene induced during a specific stage of spermatogenesis. Biol. Reprod. 70:106-113 (2004). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12954732]
Jetten, A.M. Recent advances in the mechanisms of action and physiological functions of the retinoid-related orphan receptors (RORs). Current Drug Targets-Inflammation & Allergy.3:395-412 (2004). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15584888]
Stapleton, C., Jaradat, M., Dixon, D., Kang,, H.S., Kim, S-C., Liao, G., Carey, M.A., Cristiano, J., Moorman, M.P., and Jetten, A.M. Enhanced susceptibility of staggerer (RORasg/sg) mice to lipopolysaccharide-induced lung inflammation. Am. J. Physiol. Lung Cell. Mol. Physiol. 289:L144-L152 (2005). [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15778248]
Kim, S-C., Kim, Y-S., and Jetten, A.M. . Nucl. Acids Res. 33:6805-6815 (2005). [Abstract][]
Nakanishi, G., Kim, Y-S., Nakajima, T., and Jetten, A.M. . J. Invest. Dermatol. 126:49-60 (2006) [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16417217]
Kang, H-S., Beak, J.Y., Kim, Y-S., and Jetten, A.M. NABP1, a novel RORg-regulated gene encoding a single-stranded nucleic acid binding protein. Biochem. J.397:89-99 (2006) [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16533169]
Jetten, A.M., and Joo, J.H. Retinoid-related Orphan Receptors (RORs): Roles in Cellular Differentiation and Development. Adv. Develop. Biol. 16:314-354 (2006)
Jaradat, M., Stapleton, C., Tilley, S., Dixon, D., McCaskill, J.M., Kang, H.S., Angers, M, Liao, G., Jetten, A.M. Modulatory role for retinoid-related orphan receptor a (RORa) in allergen-induced lung inflammation. Am. J. Resp. Crit. Care Med.174:1299-309 (2006) [Abstract][http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16973978]
Jetten AM, Joo JH. Retinoid-related Orphan Receptors (RORs): Roles in cellular differentiation and development. Advances in Developmental Biology 313-355 (2006). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=)
Tilley, S., Jaradat, M., Stapleton, C., Dixon, D., Kim, S-C., Erikson, C.J., McCaskill, J.M., Liao, G., Koller, B.H., and Jetten, A.M. Reduced Susceptibility to Allergen-induced Airway Inflammation in Mice Deficient in Retinoid-related Orphan Receptor (ROR) g. J. Immunol. 178:3208-3218 (2007)
Lee, S-J., Perara, L., Coulter, S., Mohrenweiser, H.W., Jetten, A.M., Goldstein, J.A. The discovery of new coding alleles of CYP26A1 which are potentially defective in the metabolism of all-trans retinoic acid metabolism and their assessment in a recombinant cDNA expression system. Pharmacogenet. Genomics. 17:169-180 (2007)
Yan, J., Kim, Y-S., Yang, X-P., Albers, M., Koegl, M., and Jetten, A.M. Ubiquitin interacting motifs of RAP80 are critical in its regulation of Estrogen Receptor a. Nucl. Acids Res. 35:1673-1686 (2007)
Kim, Y-S., Kang, H.S., and Jetten, A.M. The Krüppel-like zinc finger protein Glis2 functions as a negative modulator of the Wnt/b-catenin signaling pathway. FEBS Letters. 581:858-864 (2007)
Joo, J.H., Liao, G., Collins, J.B., Grissom, S.F., and Jetten, A.M. Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum (ER) stress response. Cancer Res.67:7929-7936 (2007)
Beak, J.Y., Kang, H.S., Kim, Y-S., and Jetten, A.M. Krüppel-like zinc finger protein Glis3 promotes osteoblast differentiation by regulating FGF18 expression. J. Bone Mineral Res.22:1234-1244 (2007)
Nurieva, R., Yang, X.O., Panopoulos, A.D., Martinez, G., Zhang, Y., Ma, L., Schluns, K., Tian, Q., Watowich, S., Jetten, A.M., and Dong, C. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature448:480-483 (2007)
Yan, J., Kim, Y-S., Yang, Y-P., Li, L-P., Liao, G., Xia, F., and Jetten, A.M. The UIM-containing protein RAP80 functions in DNA damage repair response. Cancer Res.67:6647-6656 (2007)
Yan, J., Yang, X-P., Kim, Y-S., Joo, J.H., and Jetten, A.M. RAP80 interacts with the SUMO-conjugating enzyme UBC9 and is a novel target for sumoylation. Biochem. Biophys. Res. Comm.362:132-128 (2007)
Kang, H.S., Angers, M., Beak, J.Y., Wu, X., Gimble, J.M., Wada, T, Xie, W., and Jetten, A.M. Gene expression profiling reveals a regulatory role for RORa and RORg in Phase I and Phase II metabolism. Physiol. Genomics31:281-294 (2007)
Beak JY, Kang HS, Kim YS, Jetten AM. Krüppel-like zinc finger protein Glis3 promotes osteoblast differentiation by regulating FGF18 expression. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 8:1234-1244 (2007). Abstract(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17488195)
Yan J, Kim Y-S, Yang X-P, Li L-P, Liao G, Xia F, Jetten AM. The UIM-containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response. Cancer Research 14:6647-6656 (2007). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17621610)
Nurieva R, Yang XO, Panopoulos AD, Martinez G, Zhang Y, Ma L, Schluns K, Tian Q, Watowich, S, Jetten AM, Dong C . Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature7152:480-483 (2007). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17581589)
Kang HS , Angers M , Beak JY, Wu X, Gimble JM, Wade T, Xie W, Collins JB, Grissom SF, Jetten AM. Gene expression profiling reveals a regulatory role for RORa and RORy in Phase I and Phase II metabolism. Physiological Genomics2:281-294 (2007). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17666523)
Beak JY, Kang HS, Kim YS, Jetten AM. Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1). Nucleic acids research36(5):1690-1702 (2008). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18263616)
Yang XO, Pappu BP, Nurieva1 R, Akimzhanov A, Kang HS, Chung Y, Ma L, Shah B, Panopoulos AD, Watowich SS, Schluns KS, Watowich SS, Tian Q, Jetten AM, Dong C. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR(alpha) and ROR(gamma). Immunity28(1):29-39 (2008). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18164222)
Yan J, Yang X-P, Kim Y-S, Jetten AM. RAP80 responds to DNA damage induced by both ionizing radiation and UV irradiation and is phosphorylated at Ser205. Cancer research68(11):4269-4276 (2008). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18519686)
Joo JH, Jetten AM. NF-kappa B-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. The Journal of biological chemistry283(24):16391-16399 (2008). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18424438)
Yang XO, Nurieva R, Martinez GJ, Kang HS, Chung Y, Pappu BP, Shah B, Chang SH, Schluns KS, Watowich SS, Feng X-H, Jetten AM, Dong C. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity29(1):44-56 (2008).
[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18585065)
Yan J, Jetten AM. RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damabe sites. Cancer letters271(2):179-190 (2008). [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18550271)