Skip CCR Main Navigation National Cancer Institute National Cancer Institute U.S. National Institutes of Health www.cancer.gov
CCR - For Our Staff| Home |

Our Science – Estes Website

Jacob D. Estes, Ph.D.

Selected Publications
1)  Denton PW, Estes JD, Sun Z, Othieno FA, Wei BL, Wege AK, Powell DA, Payne D, Haase AT, Garcia JV.
Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice.
PLoS Med. 5: e16, 2008. [Journal]
2)  Klatt NR, Villinger F, Bostik P, Gordon SN, Pereira L, Engram JC, Mayne A, Dunham RM, Lawson B, Ratcliffe SJ, Sodora DL, Else J, Reimann K, Staprans SI, Haase AT, Estes JD, Silvestri G, Ansari AA.
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.
J. Clin. Invest. 118: 2039-49, 2008. [Journal]
3)  Keele BF, Tazi L, Gartner S, Liu Y, Burgon TB, Estes JD, Thacker TC, Crandall KA, McArthur JC, Burton GF.
Characterization of the follicular dendritic cell reservoir of human immunodeficiency virus type 1.
J. Virol. 82: 5548-61, 2008. [Journal]
4)  Estes JD, Gordon SN, Zeng M, Chahroudi AM, Dunham RM, Staprans SI, Reilly CS, Silvestri G, Haase AT.
Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques.
J. Immunol. 180: 6798-807, 2008. [Journal]
5)  Wege AK, Melkus MW, Denton PW, Estes JD, Garcia JV.
Functional and phenotypic characterization of the humanized BLT mouse model.
Curr. Top. Microbiol. Immunol. 324: 149-65, 2008. [Journal]
6)  Li Q, Estes JD, Duan L, Jessurun J, Pambuccian S, Forster C, Wietgrefe S, Zupancic M, Schacker T, Reilly C, Carlis JV, Haase AT.
Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection.
J. Infect. Dis. 197: 420-9, 2008. [Journal]
7)  Estes JD, Haase AT, Schacker TW.
The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche.
Semin. Immunol. 2008. [Journal]
8)  Sun Z, Denton PW, Estes JD, Othieno FA, Wei BL, Wege AK, Melkus MW, Padgett-Thomas A, Zupancic M, Haase AT, Garcia JV.
Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1.
J. Exp. Med. 204: 705-14, 2007. [Journal]
9)  Estes JD, Wietgrefe S, Schacker T, Southern P, Beilman G, Reilly C, Milush JM, Lifson JD, Sodora DL, Carlis JV, Haase AT.
Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection.
J. Infect. Dis. 195: 551-61, 2007. [Journal]
10)  Melkus MW, Estes JD, Padgett-Thomas A, Gatlin J, Denton PW, Othieno FA, Wege AK, Haase AT, Garcia JV.
Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.
Nat. Med. 12: 1316-22, 2006. [Journal]
11)  Estes JD, Li Q, Reynolds MR, Wietgrefe S, Duan L, Schacker T, Picker LJ, Watkins DI, Lifson JD, Reilly C, Carlis J, Haase AT.
Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection.
J. Infect. Dis. 193: 703-12, 2006. [Journal]
12)  Li Q, Duan L, Estes JD, Ma ZM, Rourke T, Wang Y, Reilly C, Carlis J, Miller CJ, Haase AT.
Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.
Nature. 434: 1148-52, 2005. [Journal]
13)  Li Q, Lifson JD, Duan L, Schacker TW, Reilly C, Carlis J, Estes JD, Haase AT.
Potential roles of follicular dendritic cell-associated osteopontin in lymphoid follicle pathology and repair and in B cell regulation in HIV-1 and SIV infection.
J. Infect. Dis. 192: 1269-76, 2005. [Journal]
14)  Estes JD, Thacker TC, Hampton DL, Kell SA, Keele BF, Palenske EA, Druey KM, Burton GF.
Follicular dendritic cell regulation of CXCR4-mediated germinal center CD4 T cell migration.
J. Immunol. 173: 6169-78, 2004. [Journal]
15)  Estes JD, Stolpman D, Olyaei A, Corless CL, Ham JM, Schwartz JM, Orloff SL.
High prevalence of potentially hepatotoxic herbal supplement use in patients with fulminant hepatic failure.
Archives of surgery (Chicago, Ill. : 1960). 138: 852-8, 2003. [Journal]
16)  Burton GF, Keele BF, Estes JD, Thacker TC, Gartner S.
Follicular dendritic cell contributions to HIV pathogenesis.
Semin. Immunol. 14: 275-84, 2002. [Journal]
17)  Estes JD, Keele BF, Tenner-Racz K, Racz P, Redd MA, Thacker TC, Jiang Y, Lloyd MJ, Gartner S, Burton GF.
Follicular dendritic cell-mediated up-regulation of CXCR4 expression on CD4 T cells and HIV pathogenesis.
J. Immunol. 169: 2313-22, 2002. [Journal]
18)  Smith-Franklin BA, Keele BF, Tew JG, Gartner S, Szakal AK, Estes JD, Thacker TC, Burton GF.
Follicular dendritic cells and the persistence of HIV infectivity: the role of antibodies and Fcgamma receptors.
J. Immunol. 168: 2408-14, 2002. [Journal]
19)  O'Brien SJ, Berman EJ, Estes JD, Gardner MB.
Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus.
J. Virol. 47: 649-51, 1983. [Journal]
20)  Bryant ML, Scott JL, Pal BK, Estes JD, Gardner MB.
Immunopathology of natural and experimental lymphomas induced by wild mouse leukemia virus.
Am. J. Pathol. 104: 272-82, 1981. [Journal]
21)  Gardner MB, Estes JD, Casagrande J, Rasheed S.
Prevention of paralysis and suppression of lymphoma in wild mice by passive immunization to congenitally transmitted murine leukemia virus.
J. Natl. Cancer Inst. 64: 359-64, 1980. [Journal]

This page was last updated on 7/23/2008.