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The Analysis of Birth Weight and Infant Mortality
An Alternative Hypothesis
By Allen J. Wilcox

Birth weight is one of the most commonly studied variables in epidemiology. It is associated with health risks ranging from infant mortality to cardiovascular disease. The usual approach assumes that birth weight is on the causal pathway to whatever health endpoint is of interest. The alternative, discussed here, is that birth weight is not causally related to health, at least on a population level.

If this is true, it has profound implications for the analysis of birth weight and infant mortality or any other health endpoint.

Much of the material on this web site has also been published as a commentary (Acrobat PDF) in the International Journal of Epidemiology (December 2001).
It is reproduced here with permission of Oxford University Press.

graphic comparing assumptions about birth weight

Web Site Purpose

  • to describe the key features of birth weight as an epidemiologic variable

  • to show the problems with low birth weight as a "cause" of infant mortality

  • to propose an alternative framework for the relation of birth weight and mortality

  • to provide an interactive program for analysis of birth weight distributions


Web Site Contents

Return to this page.
  A tutorial discussing the underlying relation of birth weight and infant mortality and its implications for epidemiologic analysis.
  An on-line program to analyze birth weight data.
  Send questions, comments, and suggestions to Dr. Wilcox.

 


baby being weighed

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Why study birth weight?


NIEHS Epidemiology Branch
Contact Dr. Wilcox | Last update February 1, 2002


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