From CTMS_WIKI

It's important to know that when we refer to caXchange, contractually it encompasses three different tools - the caXchange ESB Hub, CTODS Lab Viewer, and the Cancer Center Hub Client (CCHC). Each of these components (and their associated documentation) are called out below.

Description

The Cancer Data Exchange (caXchange) system is part of the caBIG Clinical Trials Suite (CCTS), an integrated, stable, and secure collection of interoperable software tools that support the management of study participant information through the clinical trial lifecycle. Version 1.0 of the suite enables management of tasks such as: screening and registering patients for accrual to clinical trials; scheduling and tracking of patient encounters during the course of a study; integrating laboratory results with the patient record; tracking and managing adverse events; capturing, storing, analyzing and routing clinical data in a meaningful manner.

caXchange is the clinical data exchange component of CCTS, providing a configurable hub for exchanging clinical trial information between applications and systems. For instance, caXchange can be used to map and transfer laboratory data from non-standard clinical care systems into a standard format suitable for receipt by clinical trials databases. Contractually, caXchange is comprised of three projects: the caXchange HUB, Lab Viewer and the Cancer Center Hub Client (CCHC).

caXchange Hub

caXchange Hub provides the CCTS suite of applications with the ability to exchange clinical trials information in an audited and controlled manner. The caXchange Hub uses standard service hub protocols and messaging formats to receive, route, log, and send messages and data between applications.

Lab Viewer

Lab Viewer is a web based application developed by leveraging the SDK generated APIs of the CTODS Lab Domain UML model. Lab Viewer allows users to view laboratory activities that are stored in the CTODS Lab Domain database. Users are allowed to search the laboratory activity records by Patient Id, Study Id, Lab Start Date, and Lab End Date. Lab Viewer also allows users to send lab data in the form of XML messages via caXchange. The message type that can be sent is a Load Lab Data message to the local CDMS application (C3D) application. CTODS Lab Viewer interface allows the user to select which labs should be loaded into the CDMS.

Cancer Center Hub Client

The Cancer Center Hub Client (CCHC) is a stand-alone desktop application. It is used to transform the lab data in the form of .CSV files and HL7V2 messages to HL7V3 message format. These HL7V3 messages are saved in the CTODS database using the Grid Services.

Documentation

Some documents are maintained as stand alone word documents, some are maintained as editable wiki pages. Select the links below to access both documentation types. For more information on caXchange, please consult our GForge Project Site.

CCTS 1.1 Release (September 2008)

CCTS DEMO Release (May 2008)

Project Team

caXhchange is a collaborative project made up of domain and technical experts from NCI-CBIIT, SAIC, ScenPro and Ekagra.

Demonstrations

• caXchange v1.0 Demonstration - given at the April 29-30, 2008 CTMS Face to Face meeting. (Note: this file is interactive and uses Adobe Flash)
• caXchange v1.0 Demonstration - MS Powerpoint only
• caXchange Brochure

Project Management

The caXchange Project Management page contains information about regular project status meetings (including teleconference and webconference information), and upcoming events, links to project management related documents.

caXchange Knowledge Base

The Knowledge Base was created to address questions and issues related to the CTMS Knowledge Center as they arise as well as to provide a historical reference of questions and issues that have previously been addressed. For the caXchange project, this knowledge base includes a set of articles that answer related questions and issues that users encounter. Topic areas include:

• Using Tool in Research - Ask questions or provide examples of real-life applications. How has the tool contributed to real-life problem solving in biomedicine?
• Installation and Configuration - Questions, tips, and lessons learned related to the set-up, installation, and configuration of the tool; Include the environment/operating system you were working with, the problem or situation you encountered, and any build/install/run tip and/or work-around that might benefit others.
• Architecture and Integration - Questions, tips, and lessons learned related to interoperability with other systems and tools, including caGrid. Include an overview of the architecture being worked with, and your questions or advice to others working with the same tool or dependent software, including any step-by-step instructions useful to people integrating similar tools and systems.
• Data Migration - Questions, tips, and lessons learned related to migrating data from a legacy system or tool to this tool.
• Workflow - Observations or questions about the tool in actual use, introducing end users to the tool, integrating the tool into existing workflows, or using it with other applications.
• Data Sharing and Security - Questions, tips, and lessons learned related to data sharing or security specifically with respect to this tool.
• Documentation - Post comments to existing documentation and/or provide input for new documentation. If you are commenting on existing documentation, please reference document you are commenting on.
• Other Questions and Comments - If your question or observation doesn't fit elsewhere, put it here!

The Knowledge Base can be browsed by article (below) or searched on through the search box (left).

Using Tool In Research

Installation and Configuration

Architecture and Integration

Data Migration

Workflow

Data Sharing and Security

Documentation

For more information related to the caXchange project, please consult the documentation below listed below:

CCTS Release 1.0 (Feb 2008)

• End User Guide
• Requirements Specification
• Use Cases
• caXchange Installation Guide.doc
• Installation Guide
• Administration Guide
• Architecture Guide

Other Questions and Comments