Agent Name |
Hexafluoroacetone |
CAS Number |
684-16-2 |
Formula |
C3-F6-O |
Major Category |
Toxic Gases & Vapors |
Synonyms |
1,1,1,3,3,3-Hexafluoro-2-propanone; 2-Propanone, 1,1,1,3,3,3-hexafluoro-; 6FK; Acetone, hexafluoro-; GC 7887; Hexafluoroacetone; Perfluoro-2-propanone; Perfluoroacetone; [ChemIDplus] UN2420 |
Category |
Corrosive Gases |
Description |
Colorless gas with a musty odor. [Note: Shipped as a liquefied compressed gas.]; [NIOSH] |
Sources/Uses |
Used in the synthesis of organic chemicals and polymers; [ACGIH] |
Comments |
In 4-hour inhalation studies of rats, 300 ppm is lethal, 200 ppm causes liver and kidney injury, and 100 ppm causes testicular damage; evidence of bone marrow injury is also seen; [ACGIH] Possible frostbite from contact with liquid; [NIOSH] Inhalation of vapor can cause pulmonary edema; A skin, eye, and respiratory tract irritant; [ICSC] |
Exposure Assessment |
Skin Designation (ACGIH) |
Yes |
TIH |
Yes |
TLV (ACGIH) |
0.1 ppm |
Lethal Concentration |
LC50 (rats) = 275 ppm/3h |
Adverse Effects |
Toxic Pneumonitis |
Yes |
Hepatotoxin |
Hepatotoxin, Secondary |
Nephrotoxin |
Yes |
Reproductive Toxin |
Yes |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,1,1,3,3,3-HEXAFLUORO-2-PROPANONE
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