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Agent Name Tetrafluoroethylene
CAS Number 116-14-3
Formula C2-F4
Major Category Other Classes
Synonyms 1,1,2,2-Tetrafluoroethylene; Ethene, tetrafluoro-; Fluoroplast 4; Perfluoroethene; Perfluoroethylene; TFE; Tetrafluoroethene; Tetrafluoroethylene; Tetrafluoroethylene monomer; UN1081; [ChemIDplus]
Category Halogenated Aliphatics
Description Colorless, odorless gas; [ACGIH]
Sources/Uses Used to produce polytetrafluoroethylene polymers (Teflon); [ACGIH]
Comments In acute animal studies, causes kidney injury at concentrations of 2000 to 6000 ppm; In chronic animal studies, causes hepatic tumors and renal degeneration at 156 ppm and malignant liver and kidney tumors at 312 ppm; [ACGIH] A simple asphyxiant at high concentrations; [NJ-HSFS] Tetrafluoroethylene is a skin irritant. [Quick CPC]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 2 ppm
Vapor Pressure 24500 mm Hg
Lethal Concentration LC50 (rats) = 40,000 ppm/4H
Flammability (NFPA) 4: burns readily
Adverse Effects
Hepatotoxin Hepatotoxin, Secondary
Nephrotoxin Yes
Other Poison Simple Asphyxiant
IARC Carcinogen Possible Carcinogen
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: TETRAFLUOROETHYLENE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: January, 2009