What Are the Signs and Symptoms of Thrombotic Thrombocytopenic Purpura?

Signs and symptoms of thrombotic thrombocytopenic purpura (TTP) are due to blood clots, a low platelet count, and damaged red blood cells.

The signs and symptoms include:

• Purplish spots called purpura on the skin or mucous membranes (such as on the mouth) due to bleeding under the skin
• Paleness or jaundice (a yellowish color of the skin or eyes)
• Feeling tired or weak
• Fever
• A fast heart rate or feeling short of breath
• Headache, speech changes, confusion, coma, stroke, or seizure
• A low amount of urine, or protein or blood in the urine

If you’ve had TTP and have any of these signs and symptoms, call your doctor right away.