Who Is At Risk for Thrombotic Thrombocytopenic
Purpura?
Thrombotic thrombocytopenic purpura (TTP) is a rare
condition. About 1,200 new cases occur each year in the United States.
Most cases of TTP are the acquired type. Acquired
TTP mostly occurs in adults, but it can affect children. The condition is seen
more often in women than in men.
Inherited TTP mainly affects newborns and children.
Most people who have inherited TTP begin to have symptoms soon after birth.
Some, however, dont have their first episode of disease until
theyre adults.
What triggers TTP isnt known, but some factors
may play a role. These include:
- Diseases and conditions such as pregnancy,
cancer, HIV, infection, and lupus
- Medical procedures such as surgery and bone
marrow transplant
- Medicines such as chemotherapy, ticlopidine,
clopidogrel, cyclosporine A, and hormone replacement therapy and estrogens
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