Physiology and Pathobiology of Organ Systems Fellowship Special Emphasis Panel [F10S]

Physiology and Pathobiology of Organ Systems

[Cardiovascular and Respiratory Sciences (CVR) Integrated Review Group]


[
F10S Roster ]

F10 reviews fellowship applications for basic and clinical aspects of respiratory, digestive, renal and cardiovascular systems (including hematology); musculoskeletal, oral, and skin sciences; and surgery, radiobiology and bioengineering. Approaches include clinical studies, animal models of disease, and in vitro studies of the physiology of these organ systems and of their function in health or disease. Examples of specific areas covered are listed below.

  • Organ system physiology and pathobiology
  • Experimental models of diseases
  • Animal and clinical studies, including exercise physiology
  • Toxicology related to digestive, respiratory, cardiovascular, musculoskeletal and renal systems
  • Neural control of circulation
  • Angiogenesis and hemostasis (platelets and coagulation)
  • Hematopoiesis, myelopoiesis, and leukemogenesis
  • Trauma and sepsis
Shared Interests:

With F02A (Behavioral Neuroscience):  Fellowship applications concerning neurotoxicology may be appropriate for F02A; fellowship applications concerning toxicology of the renal, digestive systems, respiratory, or cardiovascular systems may be appropriate for F10.

With F05 (Cell Biology and Development):  Fellowship applications that utilize stem or differentiated cells to elucidate fundamental aspects of cell structure, function and regulation may be reviewed in F05; fellowship applications that concern the structure and function of differentiated cells in a tissue, organ, or pathology context may be reviewed in F10.

With F06 (Endocrinology, Nutritional Metabolism, and Reproductive Sciences): Shared interests exist in the areas of exercise physiology, renal pathophysiology, and lipoprotein metabolism. Exercise physiology in the context of skeletal muscle functions related to insulin action, insulin resistance and type 2 diabetes may be assigned to F06; exercise physiology in the context of respiratory function and regulation may be assigned to F10. Studies that focus on effects of nutrient metabolism in diabetic nephropathy and other diabetes-induced metabolic abnormalities may be assigned to F06; studies that focus on the underlying pathophysiology of the process of renal derangement and of muscle physiology addressing the role of actin and myosin and other factors in muscle contractility may be assigned to F10. In addition, F10 may be assigned applications on renal transport mechanisms intrinsic to diabetic nephropathy, diabetes-induced renal pathology, diabetes-induced urology pathology, and organ or environmental toxicology. Studies that focus on the lipoprotein risk factors or the nutrient/metabolic fate of substances in the context of type 2 diabetes and obesity may be assigned to F06; studies that focus on lipoprotein metabolism in the context of coronary artery diseases, vessel wall biology, and pathogenesis of atherosclerosis may be assigned to F10.

With F07 (Immunology): Fellowship applications that have a considerable immune component, are related to broader issues in autoimmune disease etiology or transplant immunology, or that have a significant immunobiology component may be considered for review in F07; fellowship applications that emphasize effects on target tissue physiology may be considered for review in F10.

With F08 (Genomics, Genetics, DNA Replication, and Gene Expression): Fellowship applications with a focus on basic prokaryotic and eukaryotic genetics and molecular biology may be appropriate for F08; fellowship applications with a focus on physiology or pathophysiology that utilize genetic and molecular biological approaches may be appropriate for F10.

With F09 (Oncological Sciences): Fellowship applications relevant to the role of angiogenesis in cancer pathobiology may be assigned to F09; fellowship applications relevant to other aspects of angiogenesis may be assigned to F10.

F13 (Infectious Diseases and Microbiology): Fellowship applications that focus on pathogens or pathogenic mechanisms, even in specific tissues/organs, could be assigned to F13.  When the focus of the application is the effect of infection on the organ, assignment could be to F10.

With F16 (Health and Health Related Behavior of Individuals and Populations): Fellowship applications that involve population-based, epidemiologic or behavioral studies of diseases, risks or protective factors, or studies of health care delivery systems would be appropriate for F16.  Fellowship applications involving underlying mechanisms of disease states or the physiology or pathophysiology of organ systems would be appropriate may be appropriate for F10.  Fellowship applications that involve population-based, epidemiologic or behavioral studies of diseases, risks or protective factors, or studies of health care delivery systems would be appropriate for F16.



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