| Agent Name |
Piperazine |
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| CAS Number |
110-85-0 |
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| Formula |
C4-H10-N2 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1,4-Diazacyclohexane; 1,4-Diethylenediamine; 1,4-Piperazine; Antiren; Asca-Trol No. 3; Diethylenediamine; Diethyleneimine; Dispermine; Entacyl; Eraverm; Eraverm (VAN); Hexahydro-1,4-diazine; Hexahydropyrazine; Lumbrical; Piperazidine; Piperazin [German]; Piperazine; Piperazine, anhydrous; Pipersol; Pyrazine hexahydride; Pyrazine, hexahydro-; Uvilon; Vermex; Worm-A-Ton; Wurmirazin; [ChemIDplus] UN2579 |
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| Category |
Amines, Heterocyclic |
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| Description |
Colorless solid, hygroscopic, with a pungent odor; [ICSC] |
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| Sources/Uses |
Piperazine salts are used as anthelmintic drugs; Also used to make corrosion inhibitors, insecticides, curing agents for polychloroprene, and antihistamines; [HSDB] |
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| Comments |
Corrosive to skin; [Quick CPC] A corrosive substance that can cause pulmonary edema; May cause skin sensitization and asthma after prolonged contact; May cause CNS injury if ingested in large amounts; [ICSC] Causes burns; Inhalation of high concentrations may produce acute pneumonitis and pulmonary edema; [MSDSonline] See "Piperazine dihydrochloride." |
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| Exposure Assessment |
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| Vapor Pressure |
0.16 mm Hg |
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| Lethal Concentration |
LC50 (mice) = 5,400 mg/m3/2h |
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| Explanatory Notes |
Flash point = 81 deg C; [CHEMINFO] |
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| Flammability (NFPA) |
2: high ambient temperature required |
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| Adverse Effects |
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| Asthma |
Yes |
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| Toxic Pneumonitis |
Yes |
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| Dermatotoxin |
Skin Burns |
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| Skin Sensitizer |
Yes |
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| Neurotoxin |
Other CNS Neurotoxin |
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| Links to Other NLM Databases |
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