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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good
Welcome to BMC Biotechnology published by BioMed Central
BMC Biotechnology is an open access journal publishing original peer-reviewed research articles in the manipulation of biological macromolecules or organisms for use in experimental procedures or in the pharmaceutical, agrobiological and allied industries.
BMC Biotechnology (ISSN 1472-6750) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
BMC Biotechnology 2008, 8 :93
The dynamics of gene expression in fruitflies can be accurately tracked during fly movement by recording green fluorescent protein with multiple cameras, making it possible to correlate complex behavior and gene activity.
BMC Biotechnology 2008, 8 :89
Providing chitosan microparticles with a coating of alginate improves their potential ability to deliver mucosal vaccines orally by both reducing the degradation of attached antigens by gastric juices and by delaying antigen release.
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Research article
A compact phage display human scFv library for selection of
antibodies to a wide variety of antigens Potjamas Pansri, Nanthnit Jaruseranee, Kuntalee Rangnoi, Peter Kristensen, Montarop Yamabhai BMC Biotechnology 2009, 9 :6 (29 [Abstract ] [Provisional PDF ]
Research article
Silica-based cationic bilayers as immunoadjuvants Nilton Lincopan, Mariana RA Santana, Eliana Faquim-Mauro, Maria Helena B da Costa, Ana M Carmona-Ribeiro BMC Biotechnology 2009, 9 :5 (19 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Gene therapy by electroporation for the treatment of chronic renal failure in companion animals Patricia A Brown, Angela M Bodles-Brakhop, Melissa A Pope, Ruxandra Draghia-Akli BMC Biotechnology 2009, 9 :4 (16 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Bacterial artificial chromosomes improve recombinant protein production in mammalian cells
Leander Blaas, Monica Musteanu, Robert Eferl, Anton Bauer, Emilio Casanova BMC Biotechnology 2009, 9 :3 (14 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Albumin fibrillization induces apoptosis via integrin/FAK/Akt pathway Chun-Yung Huang, Chi-Ming Liang, Chiao-Li Chu, Shu-Mei Liang BMC Biotechnology 2009, 9 :2 (8 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice Irene Bergwerf, Nathalie De Vocht, Bart Tambuyzer, Jacob Verschueren, Kristien Reekmans, Jasmijn Daans, Abdelilah Ibrahimi, Viggo Van Tendeloo, Shyama Chatterjee, Herman Goossens, Philippe G Jorens, Veerle Baekelandt, Dirk Ysebaert, Eric Van Marck, Zwi N Berneman, Annemie Van Der Linden, Peter Ponsaerts BMC Biotechnology 2009, 9 :1 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Single-chain Fv phage display propensity exhibits strong positive correlation with overall expression levels Nathan Scott, Catherine B Reynolds, Michael J Wright, Omar Qazi, Neil Fairweather, Mahendra P Deonarain BMC Biotechnology 2008, 8 :97 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A modeling study by response surface methodology and artificial neural network on culture parameters optimization for thermostable lipase production from a newly isolated thermophilic Geobacillus sp. strain ARM Afshin Ebrahimpour, Raja Noor Zaliha Raja Abd. Rahman, Diana Hooi Ean Ch'ng, Mahiran Basri, Abu Bakar Salleh BMC Biotechnology 2008, 8 :96 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Hairy-root organ cultures for the production of human acetylcholinesterase Ryan R Woods, Brian C Geyer, Tsafrir S Mor BMC Biotechnology 2008, 8 :95 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Better estimation of protein-DNA interaction parameters improve prediction of functional sites Vijayalakshmi H Nagaraj, Ruadhan A O'Flanagan, Anirvan M Sengupta BMC Biotechnology 2008, 8 :94 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Metabolite profiling studies in Saccharomyces cerevisiae: an assisting tool to prioritize host targets for antiviral drug screening Konstantin Schneider, Jens Olaf Kromer, Christoph Wittmann, Isabel Alves-Rodriguez, Andreas Meyerhans, Juana Diez, Elmar Heinzle Microbial Cell Factories 2009, 8 :12 (30 [Abstract ] [Provisional PDF ]
Research
Export of recombinant proteins in Escherichia coli using ABC transporter with an attached lipase ABC transporter recognition domain (LARD) Chan Woo Chung, Jinsun You, Kyeongyeon Kim, Yuseok Moon, Hoeon Kim, Jung Hoon Ahn Microbial Cell Factories 2009, 8 :11 (29 [Abstract ] [Provisional PDF ]
Research
Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield Nicklas Bonander, Richard AJ Darby, Ljuban Grgic, Nagamani Bora, Jikai Wen, Saverio Brogna, David R Poyner, Michael AA O'Neill, Roslyn M Bill Microbial Cell Factories 2009, 8 :10 (29 [Abstract ] [Provisional PDF ]
Research article
Construction of 12 EST libraries and characterization of a 12,226 EST dataset for chicory (Cichorium intybus) root, leaves and nodules in the context of carbohydrate metabolism investigation Nicolas Dauchot, Dominique Mingeot, Benedicte Purnelle, Celine Muys, Bernard Watillon, Marc Boutry, Pierre Van Cutsem BMC Plant Biology 2009, 9 :14 (28 [Abstract ] [Provisional PDF ]
Research article
Eukaryotic protein production in designed storage organelles Margarita Torrent, Blanca Llompart, Sabine Lasserre-Ramassamy, Immaculada Llop-Tous, Miriam Bastida, Pau Marzabal, Ann Westerholm-Pavinen, Markku Saloheimo, Peter B Heifetz, M Dolors Ludevid BMC Biology 2009, 7 :5 (28 [Abstract ] [Provisional PDF ]
Correction
Correction: A pragmatic cluster randomised controlled trial to evaluate the safety, clinical effectiveness, cost effectiveness and satisfaction with point of care testing in a general practice setting - rationale, design and baseline characteristics Caroline Laurence, Angela Gialamas, Lisa Yelland, Tanya Bubner, Philip Ryan, Kristyn Willson, Briony Glastonbury, Janice Gill, Mark Shephard, Justin Beilby Trials 2009, 10 :7 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Review
Use of folding modulators to improve heterologous protein production in Escherichia coli Olga Kolaj, Stefania Spada, Sylvain Robin, J. Gerard Wall Microbial Cell Factories 2009, 8 :9 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Consensus siRNA for inhibition of HCV genotype-4 replication Abdel Rahman N Zekri, Abeer A Bahnassy, Hanaa M Alam El-Din, Hosny M Salama Virology Journal 2009, 6 :13 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Conditional embryonic lethality to improve the sterile insect technique in Ceratitis capitata (Diptera: Tephritidae) Marc F Schetelig, Carlos Caceres, Antigone Zacharopoulou, Gerald Franz, Ernst A. Wimmer BMC Biology 2009, 7 :4 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Technical Notes
Facile promoter deletion in Escherichia coli in response to leaky expression of very robust and benign proteins from common expression vectors Martin Kawe, Uwe Horn, Andreas Pluckthun Microbial Cell Factories 2009, 8 :8 (26 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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