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Chimpanzee Genome Sequencing: Pan troglodytes

In early 2002, the National Human Genome Research Institute (NHGRI) agreed to support a chimpanzee genome sequencing project initially aimed at producing 6- to 8-fold, whole genome shotgun sequence coverage of the chimpanzee (Pan troglodytes) genome. A short time later, in late 2003, a decision was made to support a proposal to complete a high-quality (6- to 8-fold coverage) genome assembly. Paired end reads from plasmids, fosmids, and BACs will be assembled and the assembly will be analyzed before a decision is made to continue sequencing to a greater depth of coverage.

Genome Sequencing Whitepaper Proposal:

• Pan troglodytes (Submitted Feb. 2002)
• Pan troglodytes (Submitted Oct. 2002)
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Project Link:

• Washington University Genome Sequencing Center [genome.wustl.edu]

Supporting Institutions:

• Broad Institute/MIT Center for Genome Research [broad.mit.edu]

Additional Resources

Sequence and Assembly

• Individual Sequence Reads:
  • NCBI Trace Archive [ncbi.nlm.nih.gov]
  • Ensembl Trace Server [trace.ensembl.org]

ESTs

• dbEST [ncbi.nlm.nih.gov]- Database of ESTs at NCBI

SNPs

• dbSNP [ncbi.nlm.nih.gov]- Database of Single Nucleotide Polymorphisms at NCBI

BAC Libraries

• Children's Hospital Oakland Research Institute (CHORI) - Chimpanzee BAC libraries:
  • CHORI-251 Chimpanzee BAC library [bacpac.chori.org]
  • RPCI - 43 Male Chimpanzee BAC Library [bacpac.chori.org]
  • CHORI-1251: Chimpanzee Fosmid Library [bacpac.chori.org]

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Last Reviewed: October 31, 2008