[IPOD Membership Roster] [IPOD Meeting Rosters]

The Integrative Physiology of Obesity and Diabetes [IPOD] Study Section reviews applications dealing with etiology and treatment of metabolic disturbances associated with obesity and diabetes, involving endocrinological, molecular/genetic, biochemical, neuroanatomical, systems biology, dietary, metabolic and integrative physiological approaches. Emphasis is on integrative systems approaches to elucidating peripheral and central regulatory pathways of carbohydrate, lipid and energy homeostasis. Specific areas covered by IPOD:

• Peripheral metabolic regulation: analysis of intermediary metabolic pathways and mitochondrial function in adipose tissue, liver and skeletal muscle related to diabetes and obesity; nutrient storage and release and communication among these three tissues; endocrine signaling among these tissues and their communication with the brain; effects of exercise and diet on metabolic processes in adipose tissue, liver and skeletal muscle.
• Central metabolic regulation: analysis of neural regulatory pathways involved in control of body composition and energy and metabolic homeostasis; central actions of peripheral signaling molecules, such as leptin and insulin; neuroanatomical, neurodevelopmental, and neuroendocrinological analysis of circuits controlling food intake, energy expenditure and peripheral metabolism.
• Cytokine, adipokines and inflammatory regulation of metabolic and energy control: effects on insulin action in adipose, liver, muscle and neural processes; cellular and molecular responses to changes in inflammation, cytokine and adipokines levels.
• Dietary and exercise influences on metabolic regulation: use of whole body metabolic and body composition analysis to monitor changes in response to diet and exercise, including stable isotope studies, DEXA, glycemic clamps, MRI analysis of metabolic flux; the effects of perinatal diet and intrauterine growth on subsequent development of diabetes and obesity in adults and the role of epigenetics in these processes.
• Hypoglycemia and counter regulatory responses: glucose sensing and neural control of counter regulatory responses; glucoregulation of neuronal activity in brain areas involved in metabolic and energy control; analysis of insulin and leptin action in the brain.

Study sections with most closely related areas of similar science listed in rank order are:

Clinical and Integrative Diabetes and Obesity [CIDO] 
Cellular Aspects of Diabetes and Obesity [CADO] 
Integrative Nutrition and Metabolic Processes [INMP] 
Neuroendocrinology, Neuroimmunology and Behavior [NNB] 
Skeletal Muscle Biology and Exercise Physiology [SMEP]