| Agent Name |
Heptachlor |
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| CAS Number |
76-44-8 |
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| Formula |
C10-H5-Cl7 |
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| Major Category |
Pesticides |
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| Synonyms |
1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene; Biarbinex; Cupincida; Drinox; E 3314; Fennotox; Heptagran; Heptamul; Heptox; Termide; Velsicol 104. |
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| Category |
Organochlorine Pesticides |
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| Description |
White to light-tan crystals with a camphor-like odor. [insecticide]; [NIOSH] |
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| Sources/Uses |
Used to kill termites, ants, and soil insects; [EXTOXNET] |
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| Comments |
High-dose animal studies show that organochlorine insecticides can cause liver injury. [LaDou, p. 553]"No evidence of hepatic injury in humans as the result of environmental contamination." [Zimmerman, p. 414] Heptachlor exposure has been associated with aplastic anemia, e.g., after domestic application for termite control, but no dose-dependent relationship was found; [ACGIH] TLV basis = liver damage; Heptachlor epoxide (1024-57-3) is apparently formed during the environmental degradation of heptachlor. [ACGIH] |
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| Restricted |
All uses cancelled in 1988; still licensed for control of fire ants in electrical transformers; [EXTOXNET] All U.S. registrations cancelled except for underground use in power lines to control fire ants; [EPA Pesticides, p. 56] |
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| Reference Link |
EXTOXNET PIP - HEPTACHLOR |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| Bioaccumulates |
Yes |
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| TLV (ACGIH) |
0.05 mg/m3 |
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| PEL (OSHA) |
0.5 mg/m3 |
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| MAK |
0.5 mg/m3, inhalable fraction |
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| IDLH (NIOSH) |
35 mg/m3 |
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| Vapor Pressure |
0.0003 mm Hg |
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| Half Life |
Heptachlor is stored mainly in fatty tissue. It could be detected in experimental rats for up to 14 weeks after cessation of exposure. [EXTOXNET] |
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| Reference Link |
ATSDR - ToxFAQs - Heptachlor and Heptachlor Epoxide |
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| Adverse Effects |
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| Anemia |
Anemia, Aplastic |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Other Poison |
Organochlorine Pesticide |
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| IARC Carcinogen |
Possible Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: HEPTACHLOR
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