Skip Navigation

HazMap: Occupational Exposure to Hazardous Agents
HazMap Home SIS Home NLM Home

as Search Agents Search Diseases Search Jobs Full Text Search


Haz-Map Home on-tab Custom Search on-tab Help on-tab Web Glossary on-tab Reference on-tab
left corner Browse Haz-Map
right corner
Agent Name n-Heptane
CAS Number 142-82-5
Formula C7-H16
Major Category Solvents
Synonyms Dipropyl methane; Dipropylmethane; Eptani [Italian]; Gettysolve-C; Heptan [Polish]; Heptanen [Dutch]; Heptyl hydride; Skellysolve C; n-Heptane; [ChemIDplus] UN1206
Category Aliphatics, Saturated
Description Colorless liquid with a gasoline-like odor; [NIOSH]
Sources/Uses "Standard for octane-rating determinations (pure normal heptane has zero octane number) anesthetic, solvent, organic synthesis, preparation of laboratory reagents." [HSDB]
Exposure Assessment
Skin Designation (ACGIH) No
TLV (ACGIH) 400 ppm
STEL (ACGIH) 500 ppm
PEL (OSHA) 500 ppm
MAK 500 ppm
IDLH (NIOSH) 750 ppm
Excerpts from Documentation for IDLHs Other human data: Inhalation of 1,000 ppm for 6 minutes was associated with slight dizziness [Patty and Yant 1929]. Exposure to 5,000 ppm for 4 minutes produced complaints of nausea, a loss of appetite, vertigo, and incoordination [Patty and Yant 1929]. A 15�minute exposure to 5,000 ppm produced a state of intoxication characterized by uncontrolled hilarity in some individuals and in others a stupor lasting for 30 minutes after the exposure [Patty and Yant 1929].
Vapor Pressure 46 mm Hg
Odor Threshold Low 40 ppm
Odor Threshold High 547 ppm
Lethal Concentration LC50 (rats) = 103,000 mg/m3/4H
Explanatory Notes Detection odor threshold from AIHA (mean = 230 ppm); Flash point = -4 deg C;
Flammability (NFPA) 3: may ignite at ambient temperature
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: HEPTANE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





Specialized Information Services   U.S. National Library of Medicine,
8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health
Privacy/Disclaimer Notice
Customer Service: tehip@teh.nlm.nih.gov
Last updated: January, 2009