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atrasentan hydrochloride
The orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective antagonist of the endothelin-A (ETA) receptor, atrasentan binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| US brand name: | | Xinlay | | | | Code names: | | (+)-A 127722
ABT-627 | | | | Chemical structure name: | | (2R,3R,4S)-4-(1,3-benzodioxo-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic Acid | | |
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