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Last Modified: 1/7/2009 First Published: 3/31/2008


1.		Phase III Randomized Study of Induction Therapy Comprising Daunorubicin Hydrochloride and Cytarabine With or Without Midostaurin Followed by Consolidation Therapy Comprising High-Dose Cytarabine and Midostaurin Followed by Continuation Therapy Comprising Midostaurin Alone in Patients With Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Active				18 to 59				NCI				CALGB-10603 CALGB 10603, EUDRACT-2006-006852-37, NCT00651261


2.		Phase II PKC412 in Aggressive Systemic Mastocytosis and Mast Cell Leukemia

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Active				18 and over				Other				HEMMPD0003 95242, HEMMPD0003, NCT00233454, Novartis 2213, NCT00233454


3.		Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Active				18 to 70				Pharmaceutical / Industry				PKC412D2201 NCT00782067


4.		Quality of Life of Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	No phase specified				Behavioral study, Natural history/Epidemiology, Treatment				Active				60 and older				Other				2004-0060 NCT00459524

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