| Agent Name |
Dichloromonofluoromethane |
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| Alternative Name |
Dichlorofluoromethane |
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| CAS Number |
75-43-4 |
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| Formula |
C-H-Cl2-F |
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| Major Category |
Solvents |
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| Synonyms |
Algofrene type 5; Arcton 7; CFC-21; Dichlorofluoromethane; Dichloromonofluoromethane; Dwuchlorofluorometan [Polish]; F 21; FC-21; Fluorocarbon 21; Fluorodichloromethane; Freon 21; Freon F 21; Genetron 21; HCFC 21; Halon 112; Methane, dichlorofluoro-; Monofluorodichloromethane; R 21 (refrigerant); Racon 21; Refrigerant 21; [ChemIDplus] UN1029 |
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| Category |
Chlorofluorocarbons |
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| Description |
Colorless gas with a slight, ether-like odor; Note: A liquid below 48 degrees F. Shipped as a liquefied compressed gas; [NIOSH] |
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| Sources/Uses |
CFC-21 has been used as a solvent, refrigerant, and propellant. [ACGIH] |
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| Comments |
See "CHLOROFLUOROCARBONS"; Possible frostbite from contact with liquid; [NIOSH] Inhalation of high concentrations may cause CNS effects; [ICSC] "The substance may have effects on the liver." [ICSC] |
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| Restricted |
See CHLOROFLUOROCARBONS |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
10 ppm |
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| PEL (OSHA) |
1000 ppm |
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| MAK |
10 ppm |
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| IDLH (NIOSH) |
5000 ppm |
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| Excerpts from Documentation for IDLHs |
In 5�minute cardiac sensitization screening tests, 2 of 12 unanesthetized dogs exposed to 10,000 ppm of dichloromonofluoromethane plus intravenous epinephrine showed evidence of serious arrhythmia; no response was noted at 5,000 ppm [Mullin 1975]. |
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| Lethal Concentration |
LC50 (rats) = 49,900 ppm/4H |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Other Poison |
Simple Asphyxiant |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DICHLOROFLUOROMETHANE
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