| Agent Name |
o-Dichlorobenzene |
|---|
| Alternative Name |
1,2-Dichlorobenzene |
|---|
| CAS Number |
95-50-1 |
|---|
| Formula |
C6-H4-Cl2 |
|---|
| Major Category |
Solvents |
|---|
| Synonyms |
1,2-Dichlorobenzene; Chloroben; Cloroben; DCB; Dichlorobenzene, ortho, liquid; Dilantin DB; Dilatin DB; Dizene; Dowtherm E; Orthodichlorobenzene; Orthodichlorobenzol; Special termite fluid; Termitkil; o-Dichlor benzol; o-Dichlorbenzol; o-Dichlorobenzene; o-Dichlorobenzol; [ChemIDplus] UN1591 |
|---|
| Category |
Chlorinated Aromatic |
|---|
| Description |
Colorless to pale-yellow liquid with a pleasant, aromatic odor.(herbicide); [NIOSH] |
|---|
| Sources/Uses |
Used as a chemical intermediate, solvent, heat transfer liquid, deodorant, and insecticide; [ACGIH] Used as a degreasing agent, a paint solvent, paint remover, a cylinder lubricant, and a solvent for waxes, gums, resins, tars, rubber, oils, and asphalts; [HSDB] |
|---|
| Comments |
Liver and kidney injury occur in animal inhalation studies. Inhalation of saturated vapor by mice results in narcosis and death. Skin sensitization can develop after occupational exposure. [ACGIH] Inhalation of high concentrations may cause CNS effects; A skin, eye, and respiratory tract irritant; [ICSC] |
|---|
| Restricted |
Cancelled: no registered pesticide products in the USA; [HSDB] |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
No |
|---|
| TLV (ACGIH) |
25 ppm |
|---|
| STEL (ACGIH) |
50 ppm |
|---|
| PEL (OSHA) | Ceiling(OSHA) = 50 ppm |
|---|
| MAK |
10 ppm |
|---|
| IDLH (NIOSH) |
200 ppm |
|---|
| Excerpts from Documentation for IDLHs |
Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by ACGIH [1971] that 1,000 ppm was fatal to guinea pigs after 20 hours [Browning 1953]. ACGIH [1971] also reported that Cameron et al. [1937] found liver damage in animals after exposure for a few hours at 50 to 800 ppm. . . . Human data: Concentrations up to 100 ppm have been reported to have caused sporadic irritation of the eyes and respiratory tract [Elkins 1959]. |
|---|
| Vapor Pressure |
1.36 mm Hg |
|---|
| Odor Threshold Low |
0.02 ppm |
|---|
| Odor Threshold High |
50 ppm |
|---|
| RD50 |
182 ppm |
|---|
| Lethal Concentration |
LCLo (rats) = 821 ppm/7H |
|---|
| Explanatory Notes |
Detection odor threshold from AIHA (mean = 0.70 ppm); Flash point = 151 deg F; |
|---|
| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
|---|
| Flammability (NFPA) |
2: high ambient temperature required |
|---|
| Adverse Effects |
|---|
| Skin Sensitizer |
Yes |
|---|
| Neurotoxin |
CNS Solvent Syndrome |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| IARC Carcinogen |
Not Classifiable |
|---|
| Links to Other NLM Databases |
|---|
| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,2-DICHLOROBENZENE
|
|---|
|
|
