| Agent Name |
1,3-Dichloropropene |
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| CAS Number |
542-75-6; 10061-01-5; 10061-02-6 |
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| Formula |
C3-H4-Cl2 |
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| Major Category |
Pesticides |
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| Synonyms |
DD-95; [Kanerva, p. 1143] DD Soil Fumigant; Telone; Vorlex; 3-Chloroallyl chloride; DCP; 1,3-Dichloro-1-propene; 1,3-Dichloropropylene; Cis-1,3-dichloropropene (10061-01-5); Trans-1,3-dichloropropene (10061-02-6); |
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| Category |
Fumigants |
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| Description |
Colorless to straw-colored liquid with a sharp, sweet, irritating, chloroform-like odor. [insecticide] [Note: Exists as mixture of cis- & trans-isomers.] [NIOSH] |
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| Sources/Uses |
Used as a soil fumigant and in organic synthesis; [ACGIH] |
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| Comments |
Liquid causes first degree burns on short exposure; [CHRIS] Rats exposed to concentrations above 2700 ppm develop severe lung, nasal, liver, and kidney injury. Prolonged exposure at 1000 ppm causes unconsciousness. [ACGIH] Allergic contact dermatitis reported in farmworkers; [Kanerva, p. 1143] Can cause lacrimation; [HSDB] A potent nephrotoxin in experimental animals; [Rosenstock, p. 576] |
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| Restricted |
Use as fumigant suspended by EPA due to toxicity. [Sullivan, p. 1053] |
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| Reference Link |
A classic case of sensitization to DD-95 |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
1 ppm |
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| Vapor Pressure |
28 mm Hg |
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| Odor Threshold Low |
1 ppm |
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| Odor Threshold High |
3 ppm |
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| Lethal Concentration |
LCLo (rats) = 1000 ppm/2H |
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| Explanatory Notes |
Odor thresholds (detection) from CHEMINFO; |
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| Half Life |
Whole body: 1-2 days; [TDR, p. 518] |
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| Reference Link |
ATSDR - ToxFAQs - 1,3-Dichloropropene |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Dermatotoxin |
Skin Burns |
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| Skin Sensitizer |
Yes |
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| Lacrimator |
Yes |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Nephrotoxin |
Yes |
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| IARC Carcinogen |
Possible Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,3-DICHLOROPROPENE
|
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