| Agent Name |
Di-sec-octyl phthalate |
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| Alternative Name |
DEHP |
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| CAS Number |
117-81-7 |
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| Formula |
C24-H38-O4 |
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| Major Category |
Plastics & Rubber |
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| Synonyms |
Diethylhexyl phthalate; Di(2-ethylhexyl)phthalate; Bis(2-ethylhexyl) 1,2-benzenedicarboxylate; Bis(2-ethylhexyl) phthalate; Bis-(2-ethylhexyl)ester kyseliny ftalove [Czech]; Bisoflex 81; Bisoflex DOP; Celluflex DOP; Compound 889; DEHP; DOF [Russian plasticizer]; Di(2-ethylhexyl) orthophthalate; Di(2-ethylhexyl) phthalate; Di(2-ethylhexyl)orthophthalate; Di(2-ethylhexyl)phthalate; Diacizer DOP; Diethylhexyl phthalate; Dioctyl phthalate; Ergoplast FDO; Ergoplast FDO-S; Etalon; Etalon (plasticizer); Ethylhexyl phthalate; Eviplast 80; Eviplast 81; Fleximel; Flexol DOP; Flexol Plasticizer DOP; Good-rite GP 264; Hatcol DOP; Hercoflex 260; Jayflex DOP; Kodaflex DEHP; Kodaflex DOP; Mollan O; Monocizer DOP; Nuoplaz DOP; Octoil; PX-138; Palatinol AH; Pittsburgh PX-138; Plasthall DOP; Platinol AH; Platinol DOP; RC Plasticizer DOP; Reomol D 79P; Reomol DOP; Sansocizer DOP; Sansocizer R 8000; Sconamoll DOP; Sicol 150; Staflex DOP; Truflex DOP; Vestinol AH; Vinicizer 80; Witcizer 312; [ChemIDplus] |
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| Category |
Phthalate Esters |
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| Description |
Colorless, oily liquid with a slight odor; [NIOSH] |
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| Sources/Uses |
Used as a plasticizer; also used in pesticides (an inert ingredient), dielectric fluids, erasable inks, and vacuum pump oils; [ACGIH] |
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| Comments |
". . . low toxicity by all routes of exposure. . ." [ACGIH] In inhalation studies of rats, no harmful effects were found. High-dose feeding studies of mice showed reversible sperm injury; also liver damage occurred. DEHP is not readily absorbed through the skin. [ATSDR ToxFAQs] In high-dose reproductive studies of rats and mice, DEHP and other phthalates cause testicular damage to males and increased fetal losses and malformations to pregnant females. [Frazier, p. 350-2] Occupational asthma in a PVC production worker was confirmed by PEF measurements. [Malo] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
5 mg/m3 |
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| PEL (OSHA) |
5 mg/m3 |
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| MAK |
10 mg/m3 |
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| IDLH (NIOSH) |
5000 mg/m3 |
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| Excerpts from Documentation for IDLHs |
Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for di�sec octyl phthalate. Since the acute oral toxicity data in animals [Autian 1973; Shibko and Blumenthal 1973; Yagi et al. 1976] indicates that di�sec octyl phthalate has low acute toxicity, the revised IDLH for di�sec octyl phthalate is 5,000 mg/m3 based on being 1,000 times the OSHA PEL of 5 mg/m3 . . . |
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| Vapor Pressure |
1.42 x 10 -07 mm Hg |
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| Explanatory Notes |
Flash point = 405 deg F; |
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| Reference Link |
ATSDR - ToxFAQs - DEHP, Di(2-ethylhexyl)phthalate |
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| Flammability (NFPA) |
1: must be preheated |
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| Adverse Effects |
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| Asthma |
Yes |
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| Reproductive Toxin |
Yes |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: BIS(2-ETHYLHEXYL)PHTHALATE
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