| Agent Name |
2,2-Dimethylbutane |
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| Alternative Name |
Neohexane |
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| CAS Number |
75-83-2 |
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| Formula |
C6-H14 |
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| Major Category |
Solvents |
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| Synonyms |
2,2-Dimethylbutane; Butane, 2,2-dimethyl-; Neohexane; [ChemIDplus] |
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| Category |
Aliphatics, Saturated |
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| Description |
Colorless liquid with mild gasoline-like odor; [ACGIH] |
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| Sources/Uses |
Used as solvents; [ACGIH] Used as a high-octane fuel and an intermediate for synthesis of organic chemicals; [Hawley] |
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| Comments |
After exposure to hexane for 10 minutes, humans experience no effect at 2000 ppm and dizziness or giddiness at 5000 ppm. Like other solvents, hexane isomers are CNS depressants and cardiac sensitizers. Isomers other than n-hexane have the same TLV-TWA. These other isomers include 2,2-dimethylbutane, 2,3-dimethylbutane, 2-methyl pentane, and 3-methyl pentane. [ACGIH] Branched hexanes are less toxic than n-hexane. Cardiac sensitization occurs in dogs inhaling neohexane at 100,000-250,000 ppm. [CHEMINFO] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Not evaluated |
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| TLV (ACGIH) |
500 ppm |
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| STEL (ACGIH) |
1000 ppm |
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| MAK |
200 ppm |
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| Vapor Pressure |
319 mm Hg |
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| Flammability (NFPA) |
3: may ignite at ambient temperature |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 2,2-DIMETHYLBUTANE
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