| Agent Name |
Diisobutyl ketone |
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| Alternative Name |
2,6-Dimethyl-4-heptanone |
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| CAS Number |
108-83-8 |
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| Formula |
C9-H18-O |
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| Major Category |
Solvents |
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| Synonyms |
2,6-Dimethyl-4-heptanone (natural);2,6-Dimethylheptan-4-one; 2,6-Dimethylheptanone; 4-Heptanone, 2,6-dimethyl-; DIBK; Diisobutyl ketone; Isobutyl ketone; Isovalerone; Valerone; s-Diisopropylacetone; sec-Diisopropyl acetone; sym-Diisopropylacetone; [ChemIDplus] UN1157 |
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| Category |
Ketones |
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| Description |
Colorless liquid with a mild, sweet odor; [NIOSH] |
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| Sources/Uses |
"Mainly used as coating solvent"; [HSDB] |
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| Comments |
Humans experience offensive irritating effects below concentrations that cause CNS depression in experimental animals. [HSDB] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
25 ppm |
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| PEL (OSHA) |
50 ppm |
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| IDLH (NIOSH) |
500 ppm |
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| Excerpts from Documentation for IDLHs |
Human data: It has been reported that a 3�hour exposure at 50 or 100 ppm caused slight irritation to the eyes, nose, and throat [Smyth et al. 1949]. |
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| Vapor Pressure |
1.65 mm Hg |
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| Odor Threshold Low |
0.11 ppm |
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| Odor Threshold High |
0.31 ppm |
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| Lethal Concentration |
LCLo (rats) = 2,000 ppm/4H |
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| Explanatory Notes |
Odor threshold (detection at 0.11 ppm and recognition at 0.31 ppm) from CHEMINFO; Flash point = 49 deg C; |
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| Flammability (NFPA) |
2: high ambient temperature required |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DIISOBUTYL KETONE
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