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doxycycline
A synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. Doxycycline binds to the 30S ribosomal subunit, possibly to the 50S ribosomal subunit as well, thereby blocking the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of protein synthesis. In addition, this agent has exhibited inhibition of collagenase activity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | Doxycycline Monohydrate | | | | US brand name: | | Vibramycin | | |
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