| Agent Name |
1,3-Benzenedimethanamine |
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| Alternative Name |
m-Xylene alpha,alpha'-diamine |
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| CAS Number |
1477-55-0 |
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| Formula |
C8-H12-N2 |
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| Major Category |
Nitrogen Compounds |
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| Synonyms |
1,3-Benzenedimethanamine; 1,3-Bis(aminomethyl)benzene; 1,3-Bis-aminomethylbenzen [Czech]; 1,3-Xylylenediamine; Methylamine, m-phenylenebis-; alpha,alpha'-Diamino-m-xylene; m-Phenylenebis(methylamine); m-Xylene-alpha,alpha'-diamine; m-Xylylendiamin [Czech]; m-Xylylenediamine; [ChemIDplus] |
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| Category |
Amines, Aromatic |
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| Description |
Colorless liquid; [NIOSH] |
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| Sources/Uses |
Curing agent for epoxy resins; [ACGIH] |
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| Comments |
In animals the undiluted liquid is corrosive, and the 50% emulsion causes severe skin irritation. Workers in plastics production have developed skin sensitization.[ACGIH] Rats exposed for 1 hour to an aerosol ranging from 1.74 to 6.04 mg/liter have lacrimation and labored breathing. Some animals die within the following 2-14 days. Necropsy findings include changes mainly to lungs, but also to the liver and kidneys. [ACGIH] Can cause severe burns; [CHEMINFO] |
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| Reference Link |
[Allergic contact eczema caused by m-xylylene-diamine in the polyurethane silk production] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| Ceiling (ACGIH) |
0.1 mg/m3 |
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| Vapor Pressure |
0.03 mm Hg |
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| Lethal Concentration |
LC50 (rats) = 700 ppm/1h |
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| Explanatory Notes |
Flash point =117 deg C; |
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| Adverse Effects |
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| Dermatotoxin |
Skin Burns |
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| Skin Sensitizer |
Yes |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 1,3-BENZENEDIMETHANAMINE
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