| Agent Name |
p-tert-Butyltoluene |
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| CAS Number |
98-51-1 |
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| Formula |
C11-H16 |
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| Major Category |
Solvents |
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| Synonyms |
1-Methyl-4-tert-butylbenzene; 1-tert-Butyl-4-methylbenzene; 4-Methyl-tert-butylbenzene; 4-tert-Butyl-1-methylbenzene; 4-tert-Butyltoluene; 8-Methylparacymene; Benzene, 1-(1,1-dimethylethyl)-4-methyl-; PTBT; TBT; Toluene, p-tert-butyl-; p-Methyl-tert-butylbenzene; p-TBT; p-t-Butyltoluene; p-tert-Butyltoluene; [ChemIDplus] UN2667 |
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| Category |
Aromatic Solvents |
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| Description |
Colorless liquid with a distinct aromatic odor; somewhat like gasoline; [NIOSH] |
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| Sources/Uses |
Used as solvent for resins and as a chemical intermediate for the chemical and pharmaceutical industries; [HSDB] |
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| Comments |
Liver injury occurs in chronic inhalation studies of experimental animals. Giddiness was observed in volunteers exposed at 160 ppm. [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
1 ppm |
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| PEL (OSHA) |
10 ppm |
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| IDLH (NIOSH) |
100 ppm |
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| Excerpts from Documentation for IDLHs |
Basis for original (SCP) IDLH: The chosen IDLH is based on the female rat 1�hour LC50 of 934 ppm reported by Hine et al. [1954]. . . . Human data: Giddiness and altered respiration have been reported in volunteers exposed to 160 ppm for 15 minutes [Hine et al. 1954]. |
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| Vapor Pressure |
0.67 mm Hg |
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| Odor Threshold Low |
5 ppm |
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| RD50 |
360 ppm |
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| Lethal Concentration |
LC50 (rats) = 165 ppm/8H |
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| Explanatory Notes |
Odor threshold (recognition) from CHEMINFO; Flash point = 136 deg F; |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 4-T-BUTYLTOLUENE
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