| Agent Name |
tert-Butyl chromate |
|---|
| CAS Number |
1189-85-1 |
|---|
| Formula |
C8-H18-Cr-O4 |
|---|
| Major Category |
Metals |
|---|
| Synonyms |
di-tert-Butyl ester of chromic acid; Bis (tert-butyl) chromate; t-Butyl chromate; [CHEMINFO] |
|---|
| Category |
Metals, Other Compounds |
|---|
| Description |
Liquid; Note: Solidifies at 23-32 degrees F; [NIOSH] |
|---|
| Sources/Uses |
Used to synthesize catalysts and other organic chemicals; also used as a curing agent for polyurethanes and polyolefins, e.g., polypropylene and polyethylene; [NIOSH Guidelines for Chemical Hazards] |
|---|
| Comments |
Can cause acid-like burns; chronic exposure may result in kidney and liver damage; [NIOSH Guidelines for Chemical Hazards] May cause irritation of the skin, eyes, and respiratory tract; May have CNS effects, e.g., drowsiness; [CAMEO] Potential respiratory tract sensitizer; [CHEMINFO] See Chromium. |
|---|
| Exposure Assessment |
|---|
| Skin Designation (ACGIH) |
Yes |
|---|
| Bioaccumulates |
Yes |
|---|
| Ceiling (ACGIH) |
0.1 mg/m3, as CrO3 |
|---|
| PEL (OSHA) | Ceiling(OSHA) = 0.1 mg/m3, as CrO3 |
|---|
| IDLH (NIOSH) |
15 mg/m3, as Cr(VI) |
|---|
| Excerpts from Documentation for IDLHs |
Very little toxicological data are available concerning the effects produced by exposure to tert�butyl chromate. Because AIHA [1965] reported that the severity of the health hazard is low for acute exposure to chromic acid, by analogy it is assumed that the hazard is also low for acute exposure to tert�butyl chromate. Therefore, the chosen IDLH is based on an analogy with chromic acid and chromates, which has an IDLH of 30 mg/m3 (as CrO3). |
|---|
| Adverse Effects |
|---|
| Asthma |
Yes |
|---|
| Dermatotoxin |
Skin Burns |
|---|
| Skin Sensitizer |
Yes |
|---|
| Neurotoxin |
Other CNS Neurotoxin |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| Nephrotoxin |
Yes |
|---|
| Reproductive Toxin |
Yes |
|---|
| IARC Carcinogen |
Known Carcinogen |
|---|
| Links to Other NLM Databases |
|---|
|
|
