| Agent Name |
2-Bromopropane |
|---|
| CAS Number |
75-26-3 |
|---|
| Formula |
C3-H7-Br |
|---|
| Major Category |
Solvents |
|---|
| Synonyms |
2-Bromopropane; Isopropyl bromide; Propane, 2-bromo-; UN2344; [ChemIDplus] 2-BP; [ACGIH] |
|---|
| Category |
Brominated Solvents |
|---|
| Description |
Clear liquid; [Hawley] |
|---|
| Sources/Uses |
Used as a freon substitute; [ChemIDplus] Used in organic synthesis; [Hawley] |
|---|
| Comments |
In 1995, an outbreak was reported in Korean electronics workers using 2-BP to degrease switches. Adverse effects were amenorrhea and severe anemia in 17/25 females and oligospermia or azospermia in 6/8 males. The work area concentration was 12.4 ppm, and some workers had skin contact. In a Chinese plant manufacturing 2-BP, 25 workers were studied. Four females exposed at >10 ppm had amenorrhea or polymenorrhea. [ACGIH] See "1-Bromopropane." |
|---|
| Exposure Assessment |
|---|
| Vapor Pressure |
216 mm Hg |
|---|
| Lethal Concentration |
LC50 (mouse) = 31,171 ppm/4H |
|---|
| Explanatory Notes |
BP = 59.5 deg C; [ChemIDplus] |
|---|
| Adverse Effects |
|---|
| Neurotoxin |
CNS Solvent Syndrome |
|---|
| Hepatotoxin |
Hepatotoxin, Secondary |
|---|
| Reproductive Toxin |
Yes |
|---|
| Links to Other NLM Databases |
|---|
|
|
