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1.		Master Protocol for Phase II-III Chemotherapy for Pancreatic Carcinoma --- PALA vs SAM (STZ/ADR/MeCCNU)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III, Phase II				Treatment				Closed				no age specified				NCI				EST-2279

Last Modified: 11/1/1989


2.		Phase II/III Study of Continuous Infusion 5-FU with vs without Weekly PALA in Patients with Advanced Colorectal Adenocarcinoma (Summary Last Modified 11/89)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III, Phase II				Treatment				Closed				any age								MAOP-5288 NCI-V89-0092

Last Modified: 9/9/2005


3.		Phase II/III Study of Various Schedules of 5-FU Alone and with Modulation by CF or PALA in Patients with Disseminated Colorectal Carcinoma

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III, Phase II				Treatment				Closed				any age				NCI				SWOG-8905

Last Modified: 7/1/1991


4.		Phase II/III Study of High-Dose 5-FU/Low-Dose MTX vs High-Dose 5-FU/Low-Dose MTX/Low-Dose PALA in Patients with Advanced Colorectal Cancer (Summary Last Modified 07/91)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III, Phase II				Treatment				Closed				any age								EORTC-40909


5.		Phase III Comparison of 5-FU vs 5-FU/PALA vs 5-FU/LEV vs 5-FU/MeCCNU/VCR/SZC vs 5-FU/TdR for Unresectable or Metastatic Colorectal Carcinoma

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Completed				no age specified				NCI				NCCTG-804651 MAYO-804651, NCCTG-80-46-51


6.		Phase III Chemotherapy with PALA, AMSA, VM-26, and NCS as Single Agents in Small Cell Lung Cancer

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				no age specified				NCI				EST-2579

Last Modified: 10/26/2007


7.		Phase III Randomized, Intergroup Comparison of 5-FU vs 5-FU/PALA vs 5-FU/Oral CF vs 5-FU/Intravenous CF vs 5-FU/IFN-A in Patients with Advanced Colorectal Adenocarcinoma

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase III				Treatment				Closed				18 and over				NCI				EST-2290 CLB-9092, E2290

Last Modified: 9/1/1988


8.		Phase I/II Chemotherapy with PALA/High-Dose MTX/5-FU plus Leukovorin Rescue in Patients with Metastatic Colorectal Carcinoma (Summary Last Modified 09/88)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II, Phase I				Treatment				Closed				18 to 90				NCI				MSKCC-8460A NCI-T84-0324W, T84-0324


9.		Phase I/II Chemotherapy with High-Dose ARA-C plus Biochemical Modulation with PALA/Thymidine in Patients with CML in Blast Crisis and Relapsed Acute Leukemia

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II, Phase I				Treatment				Closed				15 and over				NCI				MDA-DM-8433 NCI-T84-0418D, T84-0418

Last Modified: 7/1/1999


10.		Phase II Study of Biochemical Modulation of 5-FU and 5-FU/CF with and without PALA in Patients with Resectable Colorectal Carcinoma (Summary Last Modified 07/1999)

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Completed				18 and over				NCI				CCCWFU-59193 NCI-T93-0137D, T93-0137

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