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buserelin
A synthetic analog of gonadotropin-releasing hormone (GnRH). Buserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of buserelin results in sustained inhibition of gonadotropin production, suppression of testicular and ovarian steroidogenesis, and reduced levels of circulating gonadotropin and gonadal steroids. Buserelin is more potent that GnRH. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

Synonyms:buserelin acetate
busereline
US brand name:Etilamide
Foreign brand names:Bigonist
Profact
Profact Depot
Receptal
Suprecur
Suprefact
Suprefact Depot
Suprefact Flakon
Abbreviation:BSRL
Code names:HOE 766
ICI 123215
S74-6766
Chemical structure names:
  • 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide luteinizing hormone-releasing factor (pig)
  • D-ser (bu(t))(6) pro(9) NEt LHRH Acetate



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