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rituximab A recombinant chimeric murine/human antibody directed against the CD20 antigen, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | C2B8 Monoclonal Antibody IDEC-C2B8 monoclonal antibody | | | US brand name: | | Rituxan | | | Foreign brand name: | | Mabthera | | | Abbreviation: | | MOAB IDEC-C2B8 | | | Code names: | | IDEC-102 IDEC-C2B8 | | |
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