| Comments |
Classified as "practically nontoxic," maneb has an oral LD50 of greater than 5000 mg/kg in rodents. [EXTOXNET] Allergic contact dermatitis in pesticide handlers is most likely due to maneb, carbofuran, carbaryl, captan, folpet, or captafol. [Marks, p. 312] The EBCDCs (ethylenebisdithiocarbamates) can cause irritant and allergic contact dermatitis. EBDCs include ferbam, vapam, maneb, mancozeb, zineb, thiram, and ziram. They are also used as rubber accelerators. Ethylene thiourea (ETU), which may contaminate EBCDCs, is carcinogenic and teratogenic in animal experiments. [LaDou, p. 565-70] In high-dose reproductive studies of animals, Maneb causes testicular damage, reduced fertility, and birth defects. [Frazier, p. 230-2] See the agent, "Ethylene thiourea." |
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