Agent Name |
Methyl silicate |
Alternative Name |
Tetramethoxysilane |
CAS Number |
681-84-5 |
Formula |
C4-H12-O4-Si |
Major Category |
Metals |
Synonyms |
MSP 150; Methyl Silicate 39; Methyl orthosilicate; Methyl silicate; Methyl silicate ((CH3)4SiO4); Methyl silicate ((MeO)4Si); Methyl silicate 28; SIT 7510.0; Silane, tetramethoxy-; Silicic acid, methyl ester of ortho-; Silicic acid, tetramethyl ester; TL 190; TMOS; TSL 8114; Tetra-methyl orthosilicate; Tetramethoxysilane; Tetramethyl silicate; Tetramethylsilikat [Czech]; [ChemIDplus] UN2606 |
Category |
Metalloids and Compounds |
Description |
Clear, colorless liquid. [Note: A solid below 28 degrees F.]; [NIOSH] |
Sources/Uses |
Used in corrosion resistant coatings and in catalysts; used to manufacture silicone; [ACGIH] |
Comments |
Severe damage to the cornea has been reported after occupational exposure. Experimental animals exposed repeatedly to 30 ppm develop respiratory disease with bronchiolar inflammation. [ACGIH] Its severe corneal toxicity is delayed by several hours, and workers have little or no immediate eye symptoms. [HSDB] Has potential to cause pulmonary edema after high inhalation exposure; May have effects on liver and kidneys; [ICSC] |
Exposure Assessment |
Skin Designation (ACGIH) |
No |
TLV (ACGIH) |
1 ppm |
Vapor Pressure |
12 mm Hg |
Lethal Concentration |
LCLo (rats) = 250 ppm/4h |
Explanatory Notes |
Flash point = 205 deg F; |
Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
Flammability (NFPA) |
3: may ignite at ambient temperature |
Adverse Effects |
Toxic Pneumonitis |
Yes |
Hepatotoxin |
Hepatotoxin, Secondary |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: TETRAMETHYL SILICATE
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