Agent Name |
alpha-Methyldopa |
CAS Number |
555-30-6 |
Formula |
C10-H13-N-O4 |
Major Category |
Other Uses |
Synonyms |
alpha-Methyl-DOPA ; L-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropionic acid; Medopa; Nr.C 2294; Presolisin; Sedometil; Sembrina; L-Methyldopa; L-alpha-Methyldopa; alpha-Methyl-L-dopa; MK 351; Presinol; 3-Hydroxy-alpha-methyl-L-tyrosine; L-2-Amino--2-methyl-3-(3,4-dihydroxyphenyl)propionic acid ; Aldometil; Aldomin; alpha Medopa; Hyperpax; Medomet; Medopren; Methoplain; L-(-)-beta-(3,4-Dihydroxyphenyl)-alpha-methylalanine; L-(-)-3-(3,4-Dihydroxyphenyl)-2-methylalanine; L-alpha-Methyl-3,4-dihydroxyphenylalanine; L-(-)-alpha-Methyl-beta-(3,4-dihydroxyphenyl)alanine; alpha-Methyl-L-3,4-dihydroxyphenylalanine; alpha-Methyl-beta-(3,4-dihydroxyphenyl)-L-alanine; AMD; Bayer 1440 L; Baypresol; Dopamet; Dopatec; Dopegyt; L-(alpha-Md); (-)-Methyldopa; 3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine; Aldomet; Methyl-DOPA; alpha-Methyldopa; [ChemFinder] |
Category |
Pharmaceuticals |
Comments |
Asthma reported in the pharmaceutical industry; [Malo] As an oral medication, methyldopa is used to treat hypertension. Many side effects have been reported after ingestion of therapeutic doses, including immune hemolytic anemia and drug-induced hepatitis. [HSDB] |
Reference Link |
Bronchial asthma due to alpha-methyldopa |
Exposure Assessment |
Skin Designation (ACGIH) |
Not evaluated |
Adverse Effects |
Asthma |
Yes |
Hepatotoxin |
Hepatotoxin, Secondary |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: METHYLDOPA
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