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filgrastim A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine human granulocyte colony-stimulating factor (G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF binds to and activates specific cell surface receptors, stimulating neutrophil progenitor proliferation and differentiation and selected neutrophil functions. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | granulocyte colony-stimulating factor Recombinant Methionyl Human Granulocyte Colony Stimulating Factor | | | US brand name: | | Neupogen | | | Abbreviations: | | G-CSF r-metHuG-CSF | | |
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